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Infection

, Volume 33, Issue 5–6, pp 397–400 | Cite as

Breakthrough Invasive Infection Due to Debaryomyces hansenii (teleomorph Candida famata) and Scopulariopsis brevicaulis in a Stem Cell Transplant Patient Receiving Liposomal Amphotericin B and Caspofungin for Suspected Aspergillosis

  • D. Wagner
  • Anna Sander
  • H. Bertz
  • J. Finke
  • W. V. Kern
Case Report

Abstract

An allogeneic stem cell transplant recipient developed pulmonary infiltrates and Aspergillus antigenemia during prophylactic low–dose liposomal amphotericin B. No response to therapy was observed after increasing the dose of liposomal amphotericin B and addition of caspofungin, and breakthrough candidemia developed. Therapy switch to voriconazole did not prevent the development of lethal septic shock. Shortly before death, Scopulariopsis brevicaulis was cultured from bronchial secretions, and positive blood cultures demonstrated persistent candidemia due to Debaryomyces hansenii, teleomorph of Candida famata.

Keywords

Stem Cell Transplant Voriconazole Aspergillosis Caspofungin Positive Blood Culture 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Urban & Vogel München 2005

Authors and Affiliations

  • D. Wagner
    • 1
  • Anna Sander
    • 2
  • H. Bertz
    • 3
  • J. Finke
    • 3
  • W. V. Kern
    • 1
  1. 1.Center for Infectious Diseases and Travel MedicineUniversity HospitalFreiburgGermany
  2. 2.Dept. of Medical MicrobiologyUniversity HospitalFreiburgGermany
  3. 3.Dept. of Hematology-OncologyUniversity HospitalFreiburgGermany

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