Infection

, Volume 30, Issue 2, pp 109–112 | Cite as

Fatal Intracerebral Hemorrhage Due to Leptospirosis

  • H. J. Theilen
  • C. Lück
  • U. Hanisch
  • M. Ragaller
Case Report

Abstract

Intracerebral hemorrhage in leptospirosis is a rare event. We report on a fatal case of intracerebral hemorrhage complicating leptospirosis in a 47-year-old sewage drain worker. Since substantial thrombocytopenia was observed during the course of the disease, postmortem autopsy was performed to further elucidate the genesis of platelet destruction. Due to immunohistological findings, immunologically mediated thrombolysis was considered responsible for thrombocytopenia, whereas no signs of disseminated intravasal coagulopathy or deranged platelet production in the bone marrow were detected.

Key Words Leptospirosis Intracerebral hemorrhage Thrombocytopenia Platelet antibodies Vasculitis 

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Copyright information

© Urban & Vogel Medien und Medizin Verlagsgesellschaft 2002

Authors and Affiliations

  • H. J. Theilen
    • 1
  • C. Lück
    • 2
  • U. Hanisch
    • 3
  • M. Ragaller
    • 1
  1. 1.Dept. of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Medical Faculty, Technical University of Dresden, Harvard Medical International Associated Institution, Fetscherstr. 74, D-01307 Dresden, Germany; e-mail: theilen@rcs.urz.tu-dresden.deGermany
  2. 2.Dept. of Medical Microbiology, University Hospital Carl Gustav Carus, Medical Faculty, Technical University of Dresden, Harvard Medical International Associated Institution, Dresden, GermanyGermany
  3. 3.Dept. of Pathology, University Hospital Carl Gustav Carus, Medical Faculty, Technical University of Dresden, Harvard Medical International Associated Institution, Dresden, GermanyGermany

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