Infection

, Volume 29, Issue 4, pp 240–242

Acute Disseminated Encephalomyelitis (ADEM) Due to Mycoplasma pneumoniae Infection in an Adolescent

  • K. Riedel
  • V.A.J. Kempf
  • A. Bechtold
  • M. Klimmer
Case Report

Abstract

A 17-year-old boy presented with a severe form of an acute disseminated encephalomyelitis (ADEM) with hemiparesis and coma after initial symptoms of a flu-like febrile infection 1 week previously. Titers against Mycoplasma pneumoniae were significantly increased in serum and cerebrospinal fluid (CSF). Detection of M. pneumoniae was achieved in the initial CSF sample using M. pneumoniae-specific PCR. The patient improved significantly on antimicrobial therapy with erythromycin and immunosupressive therapy with immunoglobulins and corticosteroids. This case report demonstrates a well-documented course of a central nervous system (CNS) infection resulting in the ADEM syndrome.

Key WordsMycoplasma pneumoniae Acute disseminated encephalomyelitis (ADEM) 

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Copyright information

© Urban & Vogel Medien und Medizin Verlagsgesellschaft 2001

Authors and Affiliations

  • K. Riedel
    • 1
  • V.A.J. Kempf
    • 1
  • A. Bechtold
    • 3
  • M. Klimmer
    • 3
  1. 1.Dept. of Medical Microbiology, Immunology and Hygiene, City Hospital Munich-Harlaching, Sanatoriumsplatz 2, D-81545 Munich, Germany; Phone: (+49/89) 6210-2481, Fax: -3024, e-mail: Kristina.riedel@gmx.deDE
  2. 2.Institute of Medical Microbiology, Eberhard-Karls-Universität Tübingen, Elfriede-Aulhorn-Str. 6, D-72076 Tübingen, GermanyDE
  3. 3.Dept. of Anaesthesiology and Intensive Care, City Hospital Munich-Harlaching, GermanyDE

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