Determination of radiation dose from patients undergoing Tc-99m Sestamibi nuclear cardiac imaging
To date, myocardial perfusion (MP) has been utilized to assess the adequacy of blood flow to the myocardium in order to determine the ischemic heart diseases. With the advent of SPECT/CT, MP became the most common investigation in the field of nuclear cardiology with more accuracy and details. Thallium-201 and Technetium-99m (Tc-99m) have been early used in cardiac nuclear imaging. Half-life of Tc-99m is 6 h, and its energy is 140 keV, while the half-life of Tl-201 is as longer as 73 h, its X-ray energies range between 69 and 81 kV in addition to gamma rays of 135 keV and 167 keV. The purpose of the present study was to explore the radiation dose rates emitted from the patients following Tc-99m sestamibi injection. To achieve that, the radiation emanated to the environment was measured at different distances from patients and various time intervals for 20 patients using GM counter. The mean radioactivity administered to the patients was 391.1 MBq (10.6 mCi), with a range between 276.8 MBq to maximum of 515.4 MBq. Radiation dose rate was found 9.07 μSv h−1 at 1 m distance from the patient’s chest level after 7.6 min, then decayed to 7.93 μSv h−1 after 36.5 min, and 7.83 μSv h−1 later to 66.4 min. It was concluded that 1 m distance from the patients sounds sensibly adequate to maintain the occupational dose within the safe limit following Tc-99m sestamibi injection, while verification of public dose rate ≤ 1 μSv h−1 at 1 m distance from the patient prolongs to 14 h following Tc-99m injection.
KeywordsRadiation dose rate Tc-99m Hospital management
Authors would like to thank the Hospital of Istanbul Okan University for cooperation in this study.
This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.
Compliance with ethical standards
Conflict of interest
All authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.
All procedures performed in the current study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration. Istanbul Okan University, Research Ethics Committee, approved this study with Decision number: 94 (Date: 09.05.2018). Ethics Committee Members: Prof. Dr. Mithat Kıyak, Prof. Dr. Mazhar Semih Baskan, Prof. Dr. Dilek Öztürk, Prof. Dr. Dilek Sirvanlı Özen, Prof. Dr. Ali Tayfun Atay, Dr. Nermin Bölükbaşı, Dr. Nihat Özaydın, Dr. Kerime Derya Beydağ
Informed consent was obtained from all individual participants included in the study.
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