Inter-occipital communication through the anterior commissure in callosal agenesis: a necessary prerequisite for normal binocularity?
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Morning Glory Disc Anomaly (MGDA), named after the morning glory flowers, is an optic disc anomaly characterized by an enlarged, funnel-shaped optic disc excavation, an annulus of chorioretinal pigmentary changes surrounding the excavation and a central glial tuft overlying the optic disc. Narrow, straight retinal blood vessels emerge from the periphery of the abnormal disc . MGDA is typically unilateral and should be distinguished from other congenital disc lesions, especially optic nerve coloboma (ONC) and peripapillary staphyloma .
In MGDA there is an important association with midline facial anomalies including hypertelorism, cleft lip and cleft palate, as well as with midline central nervous system anomalies such as basal encephalocele, pituitary gland abnormalities and agenesis of the corpus callosum .
Cerebral midline pathology is strongly associated with strabismus . Partial decussation at the optic chiasm in binocular mammals with front facing eyes...
The authors did not receive funding for this study.
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Conflict of interest
The authors have no conflict of interest to disclose.
All procedures performed were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and later amendments.
Informed consent was obtained.