An adult case of metapneumovirus-induced acute encephalitis
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Human metapneumovirus (HMPV) is a single negative-stranded RNA-enveloped virus in the Paramyxoviridae family . HMPV is known to cause respiratory tract infections. HMPV-induced encephalitis has only sporadically been documented, mostly in children . In adults only three former reports exist [1, 3, 4].
An 78-year-old Caucasian male patient presented at the emergency department because of agitation and confusion. His wife reported myoclonic jerks and urinary incontinence during sleep. Glasgow coma scale was 9/15. He had not taken any psychotropic drugs. Clinical examination showed no lateralisation, plantar reflexes were in flexion. The right eye was red and slightly swollen. Cardiovascular parameters were normal. Temperature was 38.9 °C. Medical history revealed diabetes mellitus type 1, arterial hypertension, hypercholesterolemia, nicotine abuse and glaucoma.
Laboratory results showed leucocytosis of 12.600 white blood cells, a normal CRP of 1 mg/l (N < 5), slightly elevated...
KeywordsMetapneumovirus Coma Encephalitis Seizures Treatment
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Conflict of interest
All the authors report no disclosure nor conflict of interest relevant to the manuscript. All authors report no financial disclosure.
This manuscript does not contain any studies with human participants or animals performed by any of the authors.
Informed consent was obtained from all individual participants included in the study. Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.
- 1.Tan YL, Wee TC (2017) Adult human metapneumovirus encephalitis: a case report highlighting challenges in clinical management and functional outcome. Med J Malays 72(6):372–373Google Scholar