An adult case of metapneumovirus-induced acute encephalitis

  • Matthias Mergeay
  • Evelien Coeckelbergh
  • Harald De CauwerEmail author
  • Mineke Viaene
  • Gerry Van der Mieren
Letter to the Editor

Human metapneumovirus (HMPV) is a single negative-stranded RNA-enveloped virus in the Paramyxoviridae family [1]. HMPV is known to cause respiratory tract infections. HMPV-induced encephalitis has only sporadically been documented, mostly in children [2]. In adults only three former reports exist [1, 3, 4].

An 78-year-old Caucasian male patient presented at the emergency department because of agitation and confusion. His wife reported myoclonic jerks and urinary incontinence during sleep. Glasgow coma scale was 9/15. He had not taken any psychotropic drugs. Clinical examination showed no lateralisation, plantar reflexes were in flexion. The right eye was red and slightly swollen. Cardiovascular parameters were normal. Temperature was 38.9 °C. Medical history revealed diabetes mellitus type 1, arterial hypertension, hypercholesterolemia, nicotine abuse and glaucoma.

Laboratory results showed leucocytosis of 12.600 white blood cells, a normal CRP of 1 mg/l (N < 5), slightly elevated...


Metapneumovirus Coma Encephalitis Seizures Treatment 


Compliance with ethical standards

Conflict of interest

All the authors report no disclosure nor conflict of interest relevant to the manuscript. All authors report no financial disclosure.

Ethical approval

This manuscript does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study. Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.


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Copyright information

© Belgian Neurological Society 2019

Authors and Affiliations

  1. 1.Department of Anesthesiology and Intensive CareAZ St DimpnaGeelBelgium
  2. 2.Department of NeurologyAZ St DimpnaGeelBelgium
  3. 3.Faculty of Medicine and Health SciencesUniversity of AntwerpWilrijkBelgium
  4. 4.Department of Emergency medicineAZ St DimpnaGeelBelgium

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