Advertisement

The clinical and radiological features of cisternal and pericallosal lipomas

  • Onur Taydas
  • Hayri OgulEmail author
  • Mecit Kantarci
Original article
  • 17 Downloads

Abstract

Purpose

To demonstrate the clinical and radiological features of pericallosal and cisternal lipomas and to compare these two groups in terms of radiological and clinical features.

Methods

This retrospective study included 23 patients diagnosed with pericallosal and cisternal lipoma between 2010 and 2017. The patients comprised 12 females and 11 males with a mean age of 38.8 years (range 12–69 years). Magnetic resonance imaging was applied to all the patients. Computed tomography (CT) was also performed in 10 patients.

Results

9 lesions were pericallosal and 14 were cisternal (7 were right quadrigeminal cistern, 3 were left quadrigeminal cistern, 1 was interpeduncular cistern, 1 was left cerebellopontine cistern, 1 was right cerebellopontine cistern, and 1 was supracerebellar cistern). The mean size of the lesions was 18.7 ± 10 mm. The shape of the lesions was curvilinear in 10 patients (43.5%) and tubulonodular in 13 patients (56.5%). The mean CT density of the lesions was − 87.7 ± 25.6 HU. The size of pericallosal lipomas (mean 27.5 mm) was statistically significantly larger than that of cisternal lipomas (mean 13.1 mm) (p = 0.001). No statistically significant difference was determined between the two groups in terms of lesion shape (p = 0.478), gender (p = 0.707), age (p = 0.639), and symptoms (p = 0.084).

Conclusions

In this study, the incidence of pericallosal lipomas was 0.011% and the incidence of cisternal lipomas was 0.017%. Although rare, the knowledge of the clinical and radiological features of pericallosal and cisternal lipomas will play an important role in the accurate diagnosis and follow-up of the patient.

Keywords

Intracranial lipoma Pericallosal lipoma Cisternal lipoma Computed tomography Magnetic resonance imaging 

Notes

Compliance with ethical standards

Conflict of interest

The authors (Onur Taydas, Hayri Ogul and Mecit Kantarci) declare no conflict of interests.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Human and/or animal studies

This article does not contain any studies with animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.

References

  1. 1.
    Friedman RB, Segal R, Latchaw RE (1986) Computerized tomographic and magnetic resonance imaging of intracranial lipoma. Case report. J Neurosurg 65(3):407–410.  https://doi.org/10.3171/jns.1986.65.3.0407 CrossRefGoogle Scholar
  2. 2.
    von Rokitansky C (1842) Lehrbuch der Pathologichen Anatomie, vol 2. Wilhelm Braumuller, ViennaGoogle Scholar
  3. 3.
    Truwit CL, Barkovich AJ (1990) Pathogenesis of intracranial lipoma: an MR study in 42 patients. AJNR Am J Neuroradiol 11(4):665–674Google Scholar
  4. 4.
    Gaskin CM, Helms CA (2004) Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. AJR Am J Roentgenol 182(3):733–739.  https://doi.org/10.2214/ajr.182.3.1820733 CrossRefGoogle Scholar
  5. 5.
    Yilmaz MB, Genc A, Egemen E, Yilmaz S, Tekiner A (2016) Pericallosal lipomas: a series of 10 cases with clinical and radiological features. Turk Neurosurg 26(3):364–368.  https://doi.org/10.5137/1019-5149.Jtn.13008-14.0 Google Scholar
  6. 6.
    Popa RT, Feier D, Fufezan O, Blaga L (2010) Interhemispheric lipoma associated with agenesis of corpus callosum in an infant: case report. Med Ultrason 12(3):249–252Google Scholar
  7. 7.
    Fandino J, Bermúdez J, Aran E (2005) Lipoma de la cisterna cuadrigémina y cisura calcarina: caso clínico y revisión de la literatura. Neurocirugia 16(2):173–176CrossRefGoogle Scholar
  8. 8.
    Gossner J (2013) Small intracranial lipomas may be a frequent finding on computed tomography of the brain. A case series. Neuroradiol J 26(1):27–29CrossRefGoogle Scholar
  9. 9.
    Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B (2006) Intracranial lipomas: importance of localization. Neuroradiology 48(1):1–7.  https://doi.org/10.1007/s00234-005-0001-z CrossRefGoogle Scholar
  10. 10.
    Jabot G, Stoquart-Elsankari S, Saliou G, Toussaint P, Deramond H, Lehmann P (2009) Intracranial lipomas: clinical appearances on neuroimaging and clinical significance. J Neurol 256(6):851–855.  https://doi.org/10.1007/s00415-009-5087-5 CrossRefGoogle Scholar
  11. 11.
    Eghwrudjakpor PO, Kurisaka M, Fukuoka M, Mori K (1992) Intracranial lipomas: current perspectives in their diagnosis and treatment. Br J Neurosurg 6(2):139–144CrossRefGoogle Scholar
  12. 12.
    Sasaki H, Yoshida K, Wakamoto H, Otani M, Toya S (1996) Lipomas of the frontal lobe. Clin Neurol Neurosurg 98(1):27–31CrossRefGoogle Scholar
  13. 13.
    Demaerel P, Van de Gaer P, Wilms G, Baert AL (1996) Interhemispheric lipoma with variable callosal dysgenesis: relationship between embryology, morphology, and symptomatology. Eur Radiol 6(6):904–909CrossRefGoogle Scholar
  14. 14.
    Seidl Z, Vaneckova M, Vitak T (2007) Intracranial lipomas: a retrospective study. Neuroradiol J 20(1):30–36.  https://doi.org/10.1177/197140090702000104 CrossRefGoogle Scholar
  15. 15.
    Mukherjee P, Street I, Irving RM (2011) Intracranial lipomas affecting the cerebellopontine angle and internal auditory canal: a case series. Otol Neurotol 32(4):670–675.  https://doi.org/10.1097/MAO.0b013e31821179e0 CrossRefGoogle Scholar
  16. 16.
    Britt PM, Bindal AK, Balko MG, Yeh HS (1993) Lipoma of the cerebral cortex: case report. Acta Neurochir (Wien) 121(1–2):88–92CrossRefGoogle Scholar
  17. 17.
    Donati F, Vassella F, Kaiser G, Blumberg A (1992) Intracranial lipomas. Neuropediatrics 23(1):32–38.  https://doi.org/10.1055/s-2008-1071309 CrossRefGoogle Scholar
  18. 18.
    Hayashi T, Shojima K, Yamamoto M, Hashimoto T, Fukuzumi A, Honda E (1983) Intracranial lipomas—report of six cases. No to shinkei = Brain nerve 35(3):257–268Google Scholar
  19. 19.
    Yilmaz MB, Egemen E, Tekiner A (2015) Lipoma of the quadrigeminal cistern: report of 12 cases with clinical and radiological features. Turk Neurosurg 25(1):16–20.  https://doi.org/10.5137/1019-5149.Jtn.8694-13.1 Google Scholar
  20. 20.
    Yilmazlar S, Kocaeli H, Aksoy K (2005) Quadrigeminal cistern lipoma. J Clin Neurosci 12(5):596–599.  https://doi.org/10.1016/j.jocn.2004.08.015 CrossRefGoogle Scholar
  21. 21.
    Jimenez Caballero PE (2012) Interhemispheric lipoma associated with agenesis of the corpus callosum. Neurologia 27(8):515–517.  https://doi.org/10.1016/j.nrl.2011.07.008 CrossRefGoogle Scholar
  22. 22.
    Duman O, Goksu E, Akyuz M, Haspolat S, Senol U (2004) Brain stem lipoma presenting as paroxysmal headache with autonomic features. Headache 44(1):105.  https://doi.org/10.1111/j.1526-4610.2004.04019.x CrossRefGoogle Scholar
  23. 23.
    Park YS, Kwon JT, Park US (2010) Interhemispheric osteolipoma with agenesis of the corpus callosum. J Korean Neurosurg Soc 47(2):148–150.  https://doi.org/10.3340/jkns.2010.47.2.148 CrossRefGoogle Scholar
  24. 24.
    Karakas E, Dogan MS, Cullu N, Kocaturk M, Kocaturk O, Karakas O, Celik B, Boyaci FN (2014) Intracranial lipomas: clinical and imaging findings. Clin Ter 165(2):e134–e138.  https://doi.org/10.7471/ct.2014.1696 Google Scholar
  25. 25.
    Feldman RP, Marcovici A, LaSala PA (2001) Intracranial lipoma of the sylvian fissure. Case report and review of the literature. J Neurosurg 94(3):515–519.  https://doi.org/10.3171/jns.2001.94.3.0515 CrossRefGoogle Scholar
  26. 26.
    Warakaulle DR, Anslow P (2003) Differential diagnosis of intracranial lesions with high signal on T1 or low signal on T2-weighted MRI. Clin Radiol 58(12):922–933CrossRefGoogle Scholar
  27. 27.
    Karantanas AH (2001) MR imaging of intracranial epidermoid tumors: specific diagnosis with Turbo-FLAIR pulse sequence. Comput Med Imaging Graph 25(3):249–255CrossRefGoogle Scholar

Copyright information

© Belgian Neurological Society 2019

Authors and Affiliations

  1. 1.Department of RadiologyErzincan Binali Yıldırım University Mengücek Gazi Training and Research HospitalErzurumTurkey
  2. 2.Department of Radiology, Medical FacultyAtaturk UniversityErzurumTurkey

Personalised recommendations