Cerebellar hemorrhage as the primary clinical manifestation of hyperacute disseminated encephalomyelitis: a case report

  • Shaoyang Sun
  • Jing Wang
  • Min Liu
  • Tao Liu
  • Yanqiang WangEmail author
Letter to the Editor


Acute disseminated encephalomyelitis (ADEM) is an acute inflammatory demyelinating encephalopathy with extensive involvement of the white matter. The clinical manifestations include headache, epileptic seizures, ataxia, quadriplegia, mental symptoms, altered consciousness and other multifocal neurological dysfunctions. Acute hemorrhagic leukoencephalitis (AHLE) is a relatively rare inflammatory demyelinating disease of the central nervous system that is considered a hyperacute type of ADEM [1]. There are no clinical reports of hyperacute ADEM in which cerebellar symptoms are the primary manifestation. We report a case of hyperacute ADEM with cerebellar hemorrhage as the primary manifestation.

Case report

A 32 year old Chinese woman underwent surgical treatment for right congenital blepharoptosis. The patient developed dizziness, vertigo and nausea that improved in the supine position by post-operative day (POD) 7. These symptoms gradually worsened and were accompanied with...



This research was supported by National Natural Science Foundation of China (No. 81870943) and Shang dong Provincial Nature Fund Joint Special Fund Project (ZR2018LH006).

Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interest related to the present work.

Ethical standard

The study was approved by the local Ethics Committee of the Affiliated Hospital of Wei fang Medical University.

Informed consent

The patient provided written informed consent for the study participation.


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Copyright information

© Belgian Neurological Society 2019

Authors and Affiliations

  • Shaoyang Sun
    • 1
  • Jing Wang
    • 1
  • Min Liu
    • 1
  • Tao Liu
    • 1
  • Yanqiang Wang
    • 2
    Email author
  1. 1.Department of NeurologyAffiliated Hospital of Qingdao UniversityQingdaoChina
  2. 2.Department of NeurologyThe Affiliated Hospital of Wei Fang Medical UniversityWeifangChina

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