Acta Neurologica Belgica

, Volume 116, Issue 4, pp 513–518 | Cite as

Factors affecting the quality of life in drug-resistant epilepsy patients

Original Article

Abstract

Epilepsy patients whose seizures cannot be controlled by treatment have a lower quality of life (QoL). The aim of the present study was to compare the potential factors affecting the QoL in patients who were seizure-free with medication or who had drug-resistant epilepsy. The study included 46 drug-resistant and 42 seizure-free epilepsy patients. The demographic and clinical features of the patients were investigated for their effects on patient QoL. The QoL was assessed by the QoL in Epilepsy Inventory-89 and depression was detected by the Beck Depression Inventory. The QoL was significantly lower in the drug-resistant patients than in the seizure-free epilepsy patients (p < 0.001). Depression, lower education level, and unemployment were associated with lower QoL scores (p < 0.001, p < 0.01, p < 0.001, respectively). After adjusting for lower education level and unemployment, depression remained as an independent factor affecting QoL (p < 0.05). In addition to their efforts to control and stop seizures, clinicians should remain aware of depression and treat it effectively to improve the QoL of drug-resistant epilepsy patients.

Keywords

Epilepsy Quality of life Depression Drug resistance 

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Copyright information

© Belgian Neurological Society 2016

Authors and Affiliations

  1. 1.Department of NeurologyTrakya University Medical FacultyEdirneTurkey
  2. 2.Department of BiostatisticsTrakya University Medical FacultyEdirneTurkey

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