Abstract
Subacute angle closure glaucoma (SACG) may lead to chronic angle closure glaucoma and irreversible vision loss. Headaches may be the sole presenting symptom. This study characterizes the medical course and symptoms of patients with SACG in whom headache was the major symptom. This retrospective observational study consisted of 30 consecutive patients, suffering from headaches and diagnosed with SACG, collected from the Glaucoma Service at the Ophthalmology Department of Meir Medical Center, Kfar Saba, Israel, a tertiary care referral facility. The primary study outcomes were reasons for referral, number of specialists visited and number of imaging studies performed before diagnosing SACG and headache characteristics. The majority of the patients experienced headaches once or twice a week. Four patients suffered a classic SACG pain involving the eye and frontal or hemicranial area. The mean time from onset of headaches to diagnosis was 2.6 years. The main reason for referral to the glaucoma clinic was consultation (53 %), and SACG was suspected by the referring physicians in two patients. Seventy-three percent of the patients were referred to at least three physicians in various medical specialties prior to referral to the glaucoma clinic. Patients usually do not volunteer history regarding headaches and clinicians often do not associate headaches with SACG in the absence of ocular symptoms. SACG should be included in the differential diagnosis in individuals older than 40 years presenting with late onset of headaches. Such patients should be referred to an ophthalmologist.
Similar content being viewed by others
References
Nesher R, Hering-Hanit R, Nesher G (2006) Subacute glaucoma masquerading as migraine. How to avoid the pitfall and make the diagnosis. Postgrad Med 119:70–73
Sihota R, Rao A, Gupta V, Srinivasan G, Sharma A (2010) Progression in primary angle closure eyes. J Glaucoma 19:632–636
Schoenen J (2001) Differential diagnosis of facial pain. Acta Neurol Belg 101:6–9
Ponka D, Kirlew M (2007) Top 10 differential diagnoses in family medicine: headache. Can Fam Physician 53:1733
Ryan CW (1996) Evaluation of patients with chronic headache. Am Fam Physician 54:1051–1057
Kumar KL (1995) Headaches. Med Clin North Am 79:261–286
Ravishankar K (2012) The art of history-taking in a headache patient. Ann Indian Acad Neurol 15:S7–S14
Nesher R, Epstein E, Stern Y, Assia E, Nesher G (2005) Headaches as the main presenting symptom of subacute angle closure glaucoma. Headache 45:172–176
Shindler KS, Sankar PS, Volpe NJ, Piltz-Seymour JR (2005) Intermittent headaches as the presenting sign of subacute angle-closure glaucoma. Neurology 65:757–758
Hollands H, Johnson D, Hollands S, Simel DL, Jinapriya D, Sharma S (2013) Do findings on routine examination identify patients at risk for primary open-angle glaucoma? JAMA 309:2035–2042
Quigley HA, Broman AT (2006) The number of persons with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267
Lewis J, Fourman S (1998) Subacute angle-closure glaucoma as a cause of headache in the presence of a white eye. Headache 38:684–686
Sawaguchi S, Sakai H, Iwase A, Yamamoto T, Abe H, Tomita G et al (2012) Prevalence of primary angle closure and primary angle-closure glaucoma in a southwestern rural population of Japan: the Kumejima study. Ophthalmology 119:1134–1142
Day AC, Baio G, Gazzard G, Bunce C, Azuara-Blanco A, Munoz B et al (2012) The prevalence of primary angle closure glaucoma in European derived populations: a systematic review. Br J Ophthalmol 96:1162–1167
Bonomi L, Marchini G, Marraffa M, Bernardi P, De Franco I, Perfetti S et al (2000) Epidemiology of angle-closure glaucoma: prevalence, clinical types, and association with peripheral anterior chamber depth in the Egna-Neumarket Glaucoma Study. Ophthalmology 107:998–1003
Friedman DS, Foster PJ, Aung T, He M (2012) Angle closure and angle-closure glaucoma: what we are doing now and what we will be doing in the future. Clin Exp Ophthalmol 40:381–387
Conflict of interest
All authors declare no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nesher, R., Mimouni, M.D., Khoury, S. et al. Delayed diagnosis of subacute angle closure glaucoma in patients presenting with headaches. Acta Neurol Belg 114, 269–272 (2014). https://doi.org/10.1007/s13760-014-0290-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13760-014-0290-2