Acta Neurologica Belgica

, Volume 113, Issue 3, pp 229–235 | Cite as

Prevalence and predictive factors for poor sleep quality among migraineurs in a tertiary hospital headache clinic

  • Zhou Zhu
  • Xiaoping Fan
  • Xuelian Li
  • Ge Tan
  • Lixue Chen
  • Jiying ZhouEmail author
Original Article


The aim of this study was to investigate the prevalence and predictive factors for poor sleep quality among migraineurs in a tertiary hospital headache clinic in southwest China. In this study, we used a visual analog scale (VAS), the Pittsburgh Sleep Quality Index (PSQI), and the Hospital Anxiety and Depression Scale (HADS) to assess headache intensity, sleep quality as well as anxiety and depression symptoms. In 211 subjects who were assessed continuously, we found that the average PSQI score was 8.03 ± 4.71, and 130 (61.61 %) migraineurs exhibited poor sleep quality (PSQI >5). Poor sleep quality was largely expressed as experiencing an extended sleep latency period, daytime dysfunction, poor subjective sleep quality, and short sleep duration. The primary factors that predicted poor sleep quality included the migraine history and comorbidity with anxiety and/or depression. Moreover, we found that most migraineurs did not adopt treatment for their poor sleep quality. Only 17 (8.06 %) patients used sleeping medication to improve their poor sleep quality; however, this medication was not effective in 16 (94.12 %) patients. Therefore, it is highly important to resolve poor sleep quality in migraineurs.


Migraine Sleep quality Predictive factors Anxiety Depression 



Pittsburgh Sleep Quality Index


Hospital Anxiety and Depression Scale


Visual analog scale


Migraine with aura


Migraine without aura



This study was supported by the National Nature Science Foundation of China (Project No. 30970988) and Natural Science Foundation Project of Chongqing Science and Technology Commission (Project No. 2011AC5201). Appreciation is expressed to the subjects for their participation.


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Copyright information

© Belgian Neurological Society 2012

Authors and Affiliations

  • Zhou Zhu
    • 1
  • Xiaoping Fan
    • 1
  • Xuelian Li
    • 1
  • Ge Tan
    • 1
  • Lixue Chen
    • 2
  • Jiying Zhou
    • 1
    Email author
  1. 1.Department of NeurologyThe First Affiliated Hospital of Chongqing Medical UniversityChongqingPeople’s Republic of China
  2. 2.Laboratory Research Center, Chongqing Key Laboratory of NeurologyThe First Affiliated Hospital of Chongqing Medical UniversityChongqingPeople’s Republic of China

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