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Acta Neurologica Belgica

, Volume 112, Issue 2, pp 199–201 | Cite as

Recurrent diplopia over a 30-year period: natural history of a Lewis and Sumner syndrome

  • Romain LefaucheurEmail author
  • Jean Paul Bouwyn
  • David Wallon
  • Anne-Laure Bedat-Millet
  • Patrick Ahtoy
  • Guillaume Perot
  • Didier Hannequin
  • David Maltête
Case Report

Abstract

We described the case of a patient with recurrent episodes of isolated diplopia over the last 30 years. On her last event, neurological examination revealed not only a right third and sixth cranial nerves involvement, but also a right peripheral facial palsy and a motor weakness on the left ulnar territory. Electrophysiological nerves motor conduction study revealed a conduction block on the left ulnar nerve and a less severe on the right ulnar nerve. Asymmetrical upper limb sensorimotor weakness combined with conduction block and cranial nerves palsy led to a diagnosis of Lewis and Sumner syndrome (LSS). This case is unusual by the presentation of the disease and is, to our knowledge the longer natural disease course of LSS reported. Moreover, it suggests that the recurrent diplopia variant may represent a separate entity with a good prognosis even in absence of invasive treatment.

Keywords

Multifocal acquired demyelinating sensory and motor neuropathy MADSAM Lewis and Sumner syndrome Oculomotor nerves 

Notes

Conflict of interest

None.

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Copyright information

© Belgian Neurological Society 2012

Authors and Affiliations

  • Romain Lefaucheur
    • 1
    Email author
  • Jean Paul Bouwyn
    • 1
  • David Wallon
    • 1
  • Anne-Laure Bedat-Millet
    • 2
  • Patrick Ahtoy
    • 1
  • Guillaume Perot
    • 3
  • Didier Hannequin
    • 1
    • 4
  • David Maltête
    • 1
    • 4
  1. 1.Department of NeurologyRouen University Hospital and University of RouenRouen CedexFrance
  2. 2.Department of NeurophysiologyRouen University Hospital and University of RouenRouenFrance
  3. 3.Department of RadiologyRouen University Hospital and University of RouenRouenFrance
  4. 4.Faculty of MedicineINSERM U614RouenFrance

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