Burnout syndrome: the effects of serotonin precursors
- 108 Downloads
‘Burnout syndrome’ is a progressive mental process whereby individuals are unable to adapt to prolonged and excessive stress at work. The main features of the syndrome are physical and emotional fatigue, depersonalization and frustration with ineffective professional and personal implementation. The first studies carried out in the 1970’s showed that this condition is much more common in the social professions employing teachers, doctors, nurses, social workers and police officers. Currently, the Maslach Burnout Inventory (MBI) is the most important medical research tool for diagnosing level of burnout. Treatment of burnout depend on the severity of the syndrome. In severe forms, in addition to socio-occupational cognitive behavioural therapy, the approach also includes drug treatment with benzodiazepines and antidepressants, particularly the selective serotonin reuptake inhibitors.
The present clinical study evaluated the effectiveness of a nutraceutical product developed in a high-technology formulation containing the metabolic precursors of serotonin and which has been used in previous clinical trials on the treatment of slight to moderate depression. The results in the present study demonstrated the effectiveness of the treatment in subjects with burnout syndrome, especially regarding their mental state, by evaluating the degree of burnout using the MBI scale and self-assessment motivational scores.
KeywordsBurnout syndrome 5-hydroxytryptophan tryptophan serotonin
Unable to display preview. Download preview PDF.
- 1.Kaschka WP, Korczak D, Broich K (2011) Burnout—a fashionable diagnosis. Dtsch Arztebl Int 108:781–787Google Scholar
- 2.Maslach C, Jackson SE (1981) Maslach Burnout Inventory (“Human Services Sur”). Consulting Psychologists Press, Palo Alto, CAGoogle Scholar
- 3.Maslach C, Schaufeli WB (1993) Historical and conceptual development of burnout. In: Schaufeli WB, Maslach C, Marek T (eds) Professional burnout: recent developments in theory and research. Taylor & Francis, New York, pp 1–16Google Scholar
- 4.Maslach C, Jackson SE, Leiter MP (1996) Maslach Burnout Inventory manual, 3rd edn. Consulting Psychologists Press, Palo Alto, CAGoogle Scholar
- 7.Freudenberger HJ (1982) Counseling and dynamics: treating the endstage person. In: Jones JW (ed) The burnout syndrome. London House Press, Park Ridge, ILGoogle Scholar
- 8.Hobfoll SE, Shirom A (2001) Conservation of resources theory: applications to stress and management in the workplace. In: Golembiewski RT (ed), Handbook of organizational behavior, 2nd ed. Marcel Dekker, New York, pp 57–80Google Scholar
- 10.Maslach C, Leiter MP (1997). The truth about burnout. Jossey Bass, San Francisco, CAGoogle Scholar
- 11.Schaufeli WB, Enzmann D (1998) The burnout companion to study and practice: a critical analysis. Taylor & Francis, LondonGoogle Scholar
- 13.American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edition, text revisionGoogle Scholar
- 15.Siegrist J, Peter R (2000) The effort-reward imbalance model. In: Schnall P, Belkic K, Landsbergis P, Baker D (eds) The workplace and cardiovascular disease. Occup Med 15:83–87Google Scholar
- 16.Rossati A, Magro G. (1999) Stress e burnout. Carocci, RomeGoogle Scholar
- 17.Hillert A, Marwitz M (2006) Die Burnout-Epidemie oder brennt die Leistungsgesellschaft aus? CH Beck, MunichGoogle Scholar
- 19.Stankov BM, Georgiev T, Gervasoni M, Fauteck JD (2007) Controlled-release formulations containing tryptophan and/or 5-hydroxytryptophan. A controlled clinical trial for mild and moderate depression. Nutrafoods 6:13–18Google Scholar
- 20.Stankov BM (2008) Controlled-release formulations containing tryptophan and/or 5-hydroxytryptophan: EP 1 637185 B1.Google Scholar
- 21.Gerev V, Pannacci M, Stankov BM, Fauteck JD (2012) Precursori della serotonina a rilascio controllato studio clinico in fumatori depressi in sovrappeso. L’Integratore Nutrizionale 15:23–27Google Scholar