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Journal of the Iranian Chemical Society

, Volume 16, Issue 5, pp 953–961 | Cite as

One-pot facile synthesis of novel 1,2,3-triazole-appended α-aminophosphonates

  • Ashruba B. Danne
  • Satish V. Akolkar
  • Tejshri R. Deshmukh
  • Madiha M. Siddiqui
  • Bapurao B. ShingateEmail author
Original Paper
  • 80 Downloads

Abstract

New α-aminophosphonates bearing 1,2,3-triazolyl moiety were easily synthesized by one-pot reaction of 1-aryl-1H-1,2,3-triazole-4-carbaldehydes, anilines and trimethyl phosphite in good to excellent yields. All the synthesized compounds were characterized by IR, 1H NMR and 13C NMR analysis. These novel 1,2,3-triazole-incorporated α-aminophosphonates may be potential biological compounds due to the presence of both important moieties, 1,2,3-triazole and aminophosphonates.

Graphical abstract

Keywords

1,2,3-Triazole α-Aminophosphonate Multicomponent reaction C–P bond formation 

Notes

Acknowledgements

The authors A.B.D. and S.V.A. are very much grateful to the University Grants Commission (UGC) and Council of Scientific and Industrial Research (CSIR), New Delhi, respectively for the award of research fellowship. The authors are also thankful to the Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431 004, India for providing laboratory facilities.

Supplementary material

13738_2018_1571_MOESM1_ESM.doc (355.5 mb)
Supplementary material 1 (DOC 364071 KB)

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Copyright information

© Iranian Chemical Society 2018

Authors and Affiliations

  • Ashruba B. Danne
    • 1
  • Satish V. Akolkar
    • 1
  • Tejshri R. Deshmukh
    • 1
  • Madiha M. Siddiqui
    • 1
  • Bapurao B. Shingate
    • 1
    Email author
  1. 1.Department of ChemistryDr. Babasaheb Ambedkar Marathwada UniversityAurangabadIndia

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