Journal of the Iranian Chemical Society

, Volume 16, Issue 1, pp 117–126 | Cite as

Eco-friendly approach to mineralise 2-nitroaniline using subcritical water oxidation method: use of ANN and RSM in the optimisation and modeling of the process

  • Erdal YabalakEmail author
  • Özgür Yilmaz
Original Paper


In this study, the mineralisation of 2-nitroaniline was investigated using the eco-friendly subcritical water oxidation method and the effective oxidising agent, H2O2. Central composite design was utilized to examine the effect of temperature, oxidant concentration, and treatment time on the mineralisation of 2-nitroaniline, to optimise the experimental process and to propose a theoretical equation of the chemical oxygen demand removal percentage. ANOVA test was performed to evaluate the reliability of the process. F and p values were obtained as 23.03 and < 0.0001, respectively. R2 and adjusted R2 were obtained as 0.9540 and 0.9126, respectively. Artificial neural network modeling was used to determine the predicted values. The efficiency of central composite design and artificial neural network was statistically compared as well as by closeness of their predicted values to the experimental values. The maximum chemical oxygen demand removal percentages of 2-nitroaniline at 473 K of temperature, 30 min of treatment time, and 30 mM of H2O2 concentration were found to be 80.15 and 78.03% according to the predicted results of central composite design and artificial neural network. Removal of 2-nitroaniline was also followed using UV–Vis, FT-IR, and NMR spectroscopy. 2-Nitroaniline was removed by 99.88% at 473 K of temperature, 90 min of treatment time, and 120 mM of H2O2. Mineralisation and removal of 2-nitroaniline were also supported by FT-IR and NMR analyses.


2-Nitroaniline Mineralisation Subcritical water Artificial neural network Response surface methodology 



This academic work was linguistically supported by the Mersin Technology Transfer Office Academic Writing Center of Mersin University.

Supplementary material

13738_2018_1487_MOESM1_ESM.docx (387 kb)
Supplementary material 1 (DOCX 386 KB)


  1. 1.
    A.G. Karunanayake, O.A. Todd, M.L. Crowley, L.B. Ricchetti, C.U. Pittman, R. Anderson, T.E. Mlsn, Chem. Eng. J. 319, 75 (2017)CrossRefGoogle Scholar
  2. 2.
    T. Heberer, Toxicol. Lett. 131, 5 (2002)CrossRefGoogle Scholar
  3. 3.
    T. Rastogi, C. Leder, K. Kuemmerer, Environ. Sci. Technol. 49, 11756 (2015)CrossRefGoogle Scholar
  4. 4.
    G. Kinrys, A.K. Gold, J.J. Worthington, A.A. Nierenberg, J. Int. Med. Res. 46, 927 (2018)CrossRefGoogle Scholar
  5. 5.
    B. Du, A.E. Price, W.C. Scott, L.A. Kristofco, A.J. Ramirez, C.K. Chambliss, J.C. Yelderman, B.W. Brooks, Sci. Total Environ. 466–467, 976 (2014)CrossRefGoogle Scholar
  6. 6.
    A. Qureshi, V. Verma, A. Kapley, H.J. Purohit, Int. Biodeterior. Biodegrad. 60, 215 (2007)CrossRefGoogle Scholar
  7. 7.
    N. Mark, J. Arthur, K. Dontsova, M. Brusseau, S. Taylor, Chemosphere 144, 1249 (2016)CrossRefGoogle Scholar
  8. 8.
    K.O. Garcia, E.C. Teixeira, D.M. Agudelo-Castañeda, M. Braga, P.G. Alabarse, F. Wiegand, Sci. Total Environ. 479–480, 57 (2014)CrossRefGoogle Scholar
  9. 9.
    C.L. He, K.L. Huang, J.H. Huang, J. Colloid Interface Sci. 342, 462 (2010)CrossRefGoogle Scholar
  10. 10.
    M.E. Mahmoud, A.E.H. Abdou, A.K. Shehata, H.M. Header, E.A. Hamed, J. Mol. Liq. 224, 1358 (2016)CrossRefGoogle Scholar
  11. 11.
    O.A. Zelekew, D.H. Kuo, Appl. Surf. Sci. 393, 110 (2017)CrossRefGoogle Scholar
  12. 12.
    P. Guo, L. Tang, J. Tang, G. Zeng, B. Huang, H. Dong, Y. Zhang, Y. Zhou, Y. Deng, L. Ma, S. Tan, J. Colloid Interface Sci. 469, 78 (2016)CrossRefGoogle Scholar
  13. 13.
    K.Q. Li, Y. Li, Z. Zheng, J. Hazard. Mater. 178, 553 (2010)CrossRefGoogle Scholar
  14. 14.
    Z.H. Farooqi, K. Naseem, R. Begum, A. Ijaz, J. Inorg. Organomet. Polym Mater. 25, 1554 (2015)CrossRefGoogle Scholar
  15. 15.
    K. Li, Z. Zheng, X. Huang, G. Zhao, J. Feng, J. Zhang, J. Hazard. Mater. 166, 213 (2009)CrossRefGoogle Scholar
  16. 16.
    Z. Dong, X. Le, X. Li, W. Zhang, C. Dong, J. Ma, Appl. Catal. B 158–159, 129 (2014)CrossRefGoogle Scholar
  17. 17.
    P. Yang, A.D. Xu, J. Xia, J. He, H.L. Xing, X.M. Zhang, S.Y. Wei, N.N. Wang, Appl. Catal. A 470, 89 (2014)CrossRefGoogle Scholar
  18. 18.
    S. Silambarasana, A.S. Vangnaia, J. Hazard. Mater. 302, 426 (2016)CrossRefGoogle Scholar
  19. 19.
    Y. Wang, Y. Zhang, G. Zhao, M. Wu, M. Li, D. Li, Y. Zhang, Y. Zhang, Sep. Purif. Technol. 104, 229 (2013)CrossRefGoogle Scholar
  20. 20.
    Y.S. Zhao, C. Sun, J.Q. Sun, R. Zhou, Sep. Purif. Technol. 142, 182 (2015)CrossRefGoogle Scholar
  21. 21.
    J.H. Sun, S.P. Sun, M.H. Fan, H.Q. Guo, Y.F. Lee, R.X. Sun, J. Hazard. Mater. 153, 187 (2008)CrossRefGoogle Scholar
  22. 22.
    L. Ding, Q. Li, D. Zhou, H. Cui, R. Tang, J. Zhai, Electrochim. Acta 77, 302 (2012)CrossRefGoogle Scholar
  23. 23.
    A. Khalid, M. Arshad, D.E. Crowley, Water Res. 43, 1110 (2009)CrossRefGoogle Scholar
  24. 24.
    S. Gautam, S.P. Kamble, S.B. Sawant, V.G. Pangarkar, Chem. Eng. J. 110, 129 (2005)CrossRefGoogle Scholar
  25. 25.
    J. Zhang, D. Shan, S. Mu, Polymer 48, 1269 (2007)CrossRefGoogle Scholar
  26. 26.
    J. Zhang, D. Shan, S. Mu, J. Polym. Sci. A Polym. Chem. 45, 5573 (2007)CrossRefGoogle Scholar
  27. 27.
    N. Wang, T. Zheng, J. Jiang, P. Wang, Chem. Eng. J. 260, 386 (2015)CrossRefGoogle Scholar
  28. 28.
    H.H. Sun, S.P. Sun, M.H. Fan, H.Q. Guo, L.P. Qiao, R.X. Sun, J. Hazard. Mater. 148, 172 (2007)CrossRefGoogle Scholar
  29. 29.
    J. Levec, A. Pintar, Catal. Today 124, 172 (2007)CrossRefGoogle Scholar
  30. 30.
    E. Yabalak, H.A. Döndaş, A.M. Gizir, J. Environ. Sci. Heal. A 52, 210 (2017)CrossRefGoogle Scholar
  31. 31.
    E. Yabalak, A.M. Gizir, J. Serb. Chem. Soc. 78, 1013 (2013)CrossRefGoogle Scholar
  32. 32.
    E. Yabalak, A.S. Könen, A. Adigüzel, R.S. Ergene, M. Tunçer, A.M. Gizir, Desalin. Water Treat. 81, 186 (2017)CrossRefGoogle Scholar
  33. 33.
    E. Yabalak, Ö Görmez, B.G. Sönmez, J. Serb. Chem. Soc. 83, 489 (2018)CrossRefGoogle Scholar
  34. 34.
    R.S. Ribeiro, A.M.T. Silva, J.L. Figueiredo, J.L. Faria, H.T. Gomes, Appl. Catal. B-Environ. 187, 428 (2016)CrossRefGoogle Scholar
  35. 35.
    P.R. Gogate, A.B. Pandit, Adv. Environ. Res. 8, 501 (2004)CrossRefGoogle Scholar
  36. 36.
    S. Daneshvar, N. Hidemi, F. Salak, N. Mahinpey, Can. J. Chem. Eng. 92, 615 (2014)CrossRefGoogle Scholar
  37. 37.
    E. Yabalak, Ö Görmez, B. Gözmen, A.M. Gizir, Int. J. Ind. Chem. 6, 23 (2015)CrossRefGoogle Scholar
  38. 38.
    N.C. Loong, M. Basri, L.F. Fang, H.R.F. Masoumi, M. Tripathy, R.A. Karjiban, E. Abdul-Malek, Ind. Crops Prod. 59, 309 (2014)CrossRefGoogle Scholar
  39. 39.
    J. Zolgharnein, A. Shahmoradi, J.B. Ghasemi, J. Chemometr. 27, 12 (2013)CrossRefGoogle Scholar
  40. 40.
    E. Yabalak, J. Enviro. Sci. Health, Part A (2018) Google Scholar
  41. 41.
    J.A. Lin, C.Hng Kuo, B.Y. Chen, Y. Li, Y.C. Liu, J.H. Chen, C.J. Shieh, Ultrason. Sonochem. 32, 258 (2016)CrossRefGoogle Scholar
  42. 42.
    K.M. Desai, S.A. Survase, P.S. Saudagar, S. Lele, R.S. Singhal, Biochem. Eng. J. 41, 266 (2008)CrossRefGoogle Scholar
  43. 43.
    K. Ameer, S.W. Bae, Y. Jo, H.G. Lee, A. Ameer, J.H. Kwon, Food Chem. 229, 198 (2017)CrossRefGoogle Scholar
  44. 44.
    C.R.T. Tarley, G. Silveira, W.N.L. dos Santos, G.D. Matos, E.G.P. da Silva, M.A. Bezerra, M. Miró, S.L.C. Ferreira, Microchem. J. 92, 58 (2009)CrossRefGoogle Scholar
  45. 45.
    Z. Zhang, H. Zheng, J. Hazard. Mater. 172, 1388 (2009)CrossRefGoogle Scholar
  46. 46.
    H. Okuyucu, A. Kurt, E. Arcaklioglu, Mater. Des. 28, 78 (2007)CrossRefGoogle Scholar
  47. 47.
    K.L. Hsu, H.V. Gupta, S. Sorooshian, Water. Resour. Res. 31, 2517 (1995)CrossRefGoogle Scholar
  48. 48.
    B. Kayan, B. Gözmen, J. Hazard. Mater. 201–202, 100 (2012)CrossRefGoogle Scholar
  49. 49.
    N.E. Jiménez Jado, C. Fernández Sánchez, J.R. Ochoa, Gómez, J. Appl. Electrochem. 34, 551 (2004)CrossRefGoogle Scholar

Copyright information

© Iranian Chemical Society 2018

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of Arts and ScienceMersin UniversityMersinTurkey

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