Development of electrochemical sensor based on molecularly imprinted copolymer for detection of nitrofurantoin
The present study aimed to identify and analyze how an imprinted molecularly sensor was used for a direct determination of nitrofurantoin (NFT). The polymerization was directly performed on the surface of glassy carbon electrode by m-dihydroxybenzene and o-aminophenol as monomers. In this regard, the most fundamental issue to be noticed was the special porous forms which, after being washed, were obtained for the NFT molecule. Accordingly, great selectivity and high sensitivity to detect NFT were observed. The proposed system showed good linearity ranging from 0.001 to 0.05 and 0.1 to 1.0 µM, with a detection limit of 0.3 nM. Finally, it should also be noted that the proposed sensor was very selective and sensitive for the detection of NFT in the real serum samples.
KeywordMolecularly imprinted polymer Electrochemical sensor Electropolymerization Nitrofurantoin
This work was supported by the research facilities of Ilam University, Ilam, Iran.
- 17.X.C. Tan, J.D. Qiu, Y. Li, X.Y. Zou, P.X. Cai, Chin. J. Anal. Chem. 32, 930 (2004)Google Scholar
- 21.L.-L. Wu, R.-P. Liang, J. Chen, J.-D. Qiu, Electrophoresis 39, 5 (2018)Google Scholar
- 22.R. Schirhagl, in Synthetic Antibodies (Springer, Berlin, 2017), pp. 325–340Google Scholar
- 31.X. Qiu, Y. Li, C. Peng, J. Instrum. Anal. 3, 14 (2018)Google Scholar