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Journal of the Iranian Chemical Society

, Volume 12, Issue 1, pp 107–111 | Cite as

Direct oxidative conversion of benzylhalides, -amines, -alcohols, and arylaldehydes to nitriles with trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane activated by NH4Br

  • Davood AzarifarEmail author
  • Zohreh Najminejad
Original Paper

Abstract

A simple and efficient oxidative conversion of benzyl derivatives of halides, amines, alcohols, and aldehydes into corresponding nitriles is described using trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane in the presence of NH4Br. The reactions proceeded smoothly at room temperature to afford the products in high-to-excellent yields.

Graphical Abstract

Keywords

Trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane DHPDMDO Oxidation Nitrile Amine Halide Alcohol Aldehyde 

Notes

Acknowledgments

The authors wish to thank the Bu-Ali Sina University Research Council for the financial support to carry out this research.

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Copyright information

© Iranian Chemical Society 2014

Authors and Affiliations

  1. 1.Department of ChemistryBu-Ali Sina UniversityHamedanIran

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