A case of acute kidney injury secondary to black cherry concentrate in a patient with chronic kidney disease secondary to type 2 diabetes mellitus

  • Mohamad MatoutEmail author
  • Alex S. Halme
  • Jeffrey Wiseman
Case Report


There are many herbal products which are accessible to patients, and they may provide with many health benefits. Nevertheless, some of these supplements can lead to significant morbidity as they can also have important side effects and impact patient’s organ systems. In this case report, we present a patient with chronic kidney disease secondary to type II diabetes mellitus who develops acute kidney injury and metabolic disturbances secondary to consuming black cherry concentrate as a mean to self-manage his gout flare. The most likely mechanism of injury was cyclooxygenase inhibition by anthocyanins, molecular compounds found in cherries that have a similar mechanism of action to nonsteroidal anti-inflammatory medications. Patient’s kidney injury and metabolic disturbances improved after the discontinuation of black cherry concentrate. This is the second case report that presents a correlation between consumption of cherry concentrate in a patient with chronic kidney disease and acute kidney injury.


Acute kidney injury Herbal medicine Chronic kidney disease Anthocyanins 



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Copyright information

© Japanese Society of Nephrology 2019

Authors and Affiliations

  1. 1.Faculty of MedicineMcGill UniversityMontrealCanada
  2. 2.McGill University Health Center, Department of MedicineMontrealCanada

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