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CEN Case Reports

, Volume 7, Issue 2, pp 264–267 | Cite as

Transplant renal vein thrombosis in a recipient with aberrant venous anatomy

  • Lyndsey Thiessen
  • Sarah MacDonell
  • Chris Wall
  • Preman Jacob
  • Ahmed Shoker
  • Michael A. J. Moser
Case Report
  • 48 Downloads

Abstract

Renal vein thrombosis in a transplanted kidney is an uncommon but critical complication that can result in graft loss if management is delayed. A 31-year-old male with known atresia of the inferior vena cava who received a deceased donor renal transplant 7 years previously presented to hospital with severe graft site pain and a week of nausea, vomiting, and chills. Serum creatinine was markedly elevated from baseline. Sonographic examination revealed external iliac vein thrombosis with extension of the thrombus into the transplant renal vein. Urgent angiographic administration of tissue plasminogen activator and suction thrombectomy was performed, then followed by heparin and clopidogrel post procedure. Within 24 h, his serum creatinine improved, and within 2 weeks returned to his baseline. He was started on lifelong warfarin anti-coagulation to reduce the risk of rethrombosis secondary to his uncorrectable aberrant venous anatomy. Due to the turbulent and sometimes reversed flow in the major veins, lifelong anticoagulation should be strongly considered for such transplant patients with recipient aberrancy of the large veins.

Keywords

Kidney transplant Veins Interventional radiology Thrombosis Anticoagulation 

Notes

Compliance with ethical standards

Conflict of interest

The authors have declared that no conflict of interest exists.

Informed consent

Informed consent was obtained from the individual included in the study.

Ethical approval

All procedures performed were in accordance with the ethical standards of the institutional research committee of the University of Saskatchewan and the Saskatoon Health Region (Bio REB#12-44).

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Copyright information

© Japanese Society of Nephrology 2018

Authors and Affiliations

  • Lyndsey Thiessen
    • 1
  • Sarah MacDonell
    • 2
  • Chris Wall
    • 2
  • Preman Jacob
    • 2
  • Ahmed Shoker
    • 3
  • Michael A. J. Moser
    • 4
  1. 1.College of MedicineUniversity of SaskatchewanSaskatoonCanada
  2. 2.Department of Radiology and Diagnostic ImagingUniversity of SaskatchewanSaskatoonCanada
  3. 3.Saskatchewan Transplant Program, Department of MedicineUniversity of SaskatchewanSaskatoonCanada
  4. 4.Saskatchewan Transplant Program, Department of SurgeryUniversity of SaskatchewanSaskatoonCanada

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