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Current Dermatology Reports

, Volume 7, Issue 3, pp 190–197 | Cite as

Urticaria, Urticarial Vasculitis, Angioedema, and Related Diseases

  • Mary Anderson
  • Tina Chu
  • Melissa M. Mauskar
Hospital- based Dermatology (D Kroshinsky, Section Editor)
  • 25 Downloads
Part of the following topical collections:
  1. Topical Collection on Hospital-based Dermatology

Abstract

Purpose of Review

Dermatologists are frequently called to evaluate patients with urticaria in the emergency room, urgent care clinics, and hospitals. Many acute urticarial eruptions will resolve without long-term sequelae; however, there are red flags that clinicians must be aware of.

Recent Findings

First-line treatment for acute urticaria is regular dose H1 antagonists; however, the dose can be increased up to fourfold for refractory disease. Short courses of corticosteroids should be avoided as rebound urticaria is common upon discontinuation. Urticarial vasculitis presents with persistent, atypical urticaria, burning, and residual lesions. The most common extra-cutaneous manifestation of urticarial vasculitis is musculoskeletal involvement. Schnitzler syndrome is a rare, severe condition but new evidence provides promise for use of biologic therapies.

Summary

Acute spontaneous urticarial eruptions are commonly encountered in hospitalized patients. This review provides readers with the tools needed to delineate benign eruptions from more concerning conditions.

Keywords

Urticaria Urticarial vasculitis Angioedema Hypocomplementemic urticarial vasculitis Hypocomplementemic urticarial vasculitis syndrome 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. 1.Department of DermatologyUT Southwestern Medical CenterDallasUSA

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