Current Obstetrics and Gynecology Reports

, Volume 3, Issue 2, pp 116–122

Role of Human Papillomavirus Testing in Screening of Cervical Neoplasia

Management of HPV and Associated Cervical Lesions (C-H Lai, Section Editor)

DOI: 10.1007/s13669-014-0078-7

Cite this article as:
Chao, A., Tang, YH. & Lai, CH. Curr Obstet Gynecol Rep (2014) 3: 116. doi:10.1007/s13669-014-0078-7


Human papillomavirus (HPV) is the causative agent of cervical intraepithelial neoplasia and cervical cancer. HPV and cytology co-tests in women aged 30 years or older every 5 years as primary cervical screening is recommended for developed countries. In HPV-positive and cytology-negative women, follow-up with co-tests at 12 months is recommended. Nevertheless, if HPV-16 or HPV-18 is positive, direct colposcopy is recommended. In mild cytological abnormality and HPV-negative women, routine screening should be continued as per age-specific guidelines. Women with history of cervical intraepithelial neoplasia grade 2 or more should be followed at least 20 years even after age 65 years. In area with very limited resource, a single visit “screen-and-treat” visual inspection with acetic acid might be reasonable. Although the policies of cervical screening vary in different regions, the future screening strategies when the young HPV vaccinated population reaches the screening age will need to be renovated.


Human papillomavirus Screening Cervix Neoplasia Management of human papillomavirus Human papillomavirus-positive Cervical cancer 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Angel Chao
    • 1
    • 2
    • 3
  • Yun-Hsin Tang
    • 1
    • 2
  • Chyong-Huey Lai
    • 1
    • 2
  1. 1.Department of Obstetrics and GynecologyChang Gung Memorial Hospital and Chang Gung UniversityTaoyuanTaiwan
  2. 2.Gynecologic Cancer Research CenterChang Gung Memorial HospitalKeelung CityTaiwan
  3. 3.Department of Obstetrics and GynecologyChang Gung Memorial Hospital Linkou Medical CenterTaoyuanTaiwan

Personalised recommendations