Multi-etiological Perspective on Child Obesity Prevention
Purpose of Review
The simple energy balance model of obesity is inconsistent with the available findings on obesity etiology, prevention, and treatment. Yet, the most commonly stated causes of pediatric obesity are predicated on this model. A more comprehensive biological model is needed upon which to base behavioral interventions aimed at obesity prevention. In this light, alternative etiologies are little investigated and thereby poorly understood.
Three candidate alternate etiologies are briefly presented: infectobesity, the gut microbiome, and circadian rhythms.
Behavioral child obesity preventive investigators need to collaborate with biological colleagues to more intensively analyze the behavioral aspects of these etiologies and to generate innovative procedures for preventing a multi-etiological problem, e.g., group risk analysis, triaging for likely causes of obesity.
KeywordsAdenovirus-36 Microbiome Circadian rhythm Children Obesity Prevention
The authors express their appreciation to the Section Editor, Alexis C. Wood, PhD, for her many important contributions in revising this manuscript.
Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health under award number K99HD091396. This work is also a publication of the United States Department of Agriculture (USDA/ARS) Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, and had been funded in part with federal funds from the USDA/ARS under Cooperative Agreement No. 58-3092-5-001.
Compliance with Ethical Standards
Conflict of Interest
Tom Baranowski, Kathleen J. Motil, and Jennette P. Moreno declare they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
The contents of this publication do not necessarily reflect the views or policies of the USDA or the National Institutes of Health, nor does mention of trade names, commercial products, or organizations imply endorsement from the US government.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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