Current Nutrition Reports

, Volume 7, Issue 3, pp 121–130 | Cite as

Impact of Energy Drinks on Health and Well-being

  • Senthilkumar Sankararaman
  • Wahid Syed
  • Valentina Medici
  • Thomas J. Sferra
Gastroenterology, Critical Care, and Lifestyle Medicine (SA McClave, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Gastroenterology, Critical Care, and Lifestyle Medicine


Purpose of Review

Energy drinks and energy shots are functional supplements with higher caffeine content marketed toward adolescents and young adults with the intention of boosting energy. Parallel to its rising popularity, there are safety concerns with the consumption of these beverages. Herein, we reviewed the impact these supplements produce on health and well-being.

Recent Findings

Most of the promoted benefits of the beverages can be attributed to caffeine. The physiologic effects, if any, of other ingredients such as vitamins and herbal extracts are unclear. The presence of a higher caffeine content as compared to soft drinks may predispose to caffeine intoxication in susceptible individuals. Also, the practice of co-ingestion of these beverages with alcohol is still prevalent and associated with serious consequences.


Strict regulations (restriction of sales, clear warning labels, capping caffeine levels) and public education may help prevent the adverse outcomes from these beverages.


Energy drinks Energy shots Supplements Caffeine Taurine 


Compliance with Ethical Standards

Conflict of Interest

Senthilkumar Sankararaman is supported by a sponsored fellowship program with the Nestlé Nutrition Institute.

Wahid Syed declares that he has no conflict of interest.

Valentina Medici declares that she has no conflict of interest.

Thomas J. Sferra declares that he has no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. 1.
    Care RP. Sports Drinks and Energy drinks for children and adolescents: are they appropriate? Pediatrics. 2011;127(6):1182–9.CrossRefGoogle Scholar
  2. 2.
    Heckman MA, Weil J, de Mejia EG. Caffeine (1, 3, 7-trimethylxanthine) in foods: a comprehensive review on consumption, functionality, safety, and regulatory matters. J Food Sci. 2010;75(3)Google Scholar
  3. 3.
    Accessed on 5.15.2018 [Internet]. Available from:
  4. 4.
    Accessed on 5.15.2018 [Internet]. Available from:
  5. 5.
    Accessed on 5.15.2018 [Internet]. Available from:
  6. 6.
    Accessed on 5.15.2018 [Internet]. Available from:
  7. 7.
    Accessed on 5.15.2018 [Internet]. Available from:
  8. 8.
    Accessed on 5.15.2018 [Internet]. Available from:
  9. 9.
    Accessed on 5.15.2018 [Internet]. Available from:
  10. 10.
    Accessed on 5.15.2018 [Internet]. Available from:
  11. 11.
    Accessed on 5.15.2018 [Internet]. Available from:
  12. 12.
  13. 13.
    Accessed on 5.15.2018 [Internet]. Available from:
  14. 14.
  15. 15.
    Accessed on 5.15.2018 [Internet]. Available from:
  16. 16.
    Enriquez A, Frankel DS. Arrhythmogenic effects of energy drinks. J Cardiovasc Electrophysiol. 2017;28(6):711–7.CrossRefPubMedGoogle Scholar
  17. 17.
    Thorlton J, Colby DA, Devine P. Proposed actions for the US food and drug administration to implement to minimize adverse effects associated with energy drink consumption. Am J Public Health. 2014;104(7):1175–80.CrossRefPubMedPubMedCentralGoogle Scholar
  18. 18.
    Lara B, Ruiz-Vicente D, Areces F, Abián-Vicén J, Salinero JJ, Gonzalez-Millán C, et al. Acute consumption of a caffeinated energy drink enhances aspects of performance in sprint swimmers. Br J Nutr. 2015;114(6):908–14.CrossRefPubMedGoogle Scholar
  19. 19.
  20. 20.
    Heckman MA, Sherry K, de Mejia EG. Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States. Compr Rev Food Sci Food Saf. 2010;9(3):303–17.CrossRefGoogle Scholar
  21. 21.
    Reissig CJ, Strain EC, Griffiths RR. Caffeinated energy drinks-a growing problem. Drug Alcohol Depend. 2009;99(1–3):1–10.CrossRefPubMedGoogle Scholar
  22. 22.
    Accessed on 5.15.2018 [Internet]. Available from:
  23. 23.
  24. 24.
    Yvonne, M. Terryn, McElrath MSA, Patrick M., O’Malley, PhD, and Lloyd D. Johnston P. Energy drinks, soft drinks, and substance use among US secondary school students. J Addict Med 2012;8(1):6–17.Google Scholar
  25. 25.
    Terry-McElrath YM, O’malley PM, Johnston LD. Energy drinks, soft drinks, and substance use among United States secondary school students. J Addict Med 8(1):6–13.Google Scholar
  26. 26.
    Manchester J, Eshel I, Marion DW. The benefits and risks of energy drinks in young adults and military service members. Mil Med. 2017;182(7):e1726–33.CrossRefPubMedGoogle Scholar
  27. 27.
    Fulgoni VL, Keast DR, Lieberman HR. Trends in intake and sources of caffeine in the diets of US adults: 2001-2010. Am J Clin Nutr. 2015;101(5):1081–7.CrossRefPubMedGoogle Scholar
  28. 28.
    Costa BM, Hayley A, Miller P. Adolescent energy drink consumption: an Australian perspective. Appetite. 2016;105:638–42.CrossRefPubMedGoogle Scholar
  29. 29.
    McLellan TM, Riviere LA, Williams KW, McGurk D, Lieberman HR. Caffeine and energy drink use by combat arms soldiers in Afghanistan as a countermeasure for sleep loss and high operational demands. Nutr Neurosci. 2018 Mar;11:1–10.CrossRefGoogle Scholar
  30. 30.
    Accessed on 5.15.2018 [Internet]. Available from:
  31. 31.
    Seifert SM, Schaechter JL, Hershorin ER, Lipshultz SE. Health effects of energy drinks on children, adolescents, and Young Adults. Pediatrics. 2011;127(3):511–28.CrossRefPubMedPubMedCentralGoogle Scholar
  32. 32.
  33. 33.
    Sepkowitz KA. Energy drinks and caffeine-related adverse effects. JAMA. 2013;309(3):243–4.CrossRefPubMedGoogle Scholar
  34. 34.
    Dawodu A, Cleaver K. Behavioural correlates of energy drink consumption among adolescents: a review of the literature. J Child Heal Care. 2017;21(4):446–62.CrossRefGoogle Scholar
  35. 35.
    Ha D, Song I, Jang G, Lee E-K, Shin J-Y. Use pattern and predictors of use of highly caffeinated energy drinks among South Korean adolescents: a study using the Health Belief Model. BMJ Open. 2017;7(9):e017224.CrossRefPubMedPubMedCentralGoogle Scholar
  36. 36.
    Hammond D, Reid JL, Zukowski S. Adverse effects of caffeinated energy drinks among youth and young adults in Canada: a Web-based survey. C open. 2018;6(1):E19–25.CrossRefGoogle Scholar
  37. 37.
    Peacock A, Bruno R, Ferris J, Winstock A. Energy drink use frequency among an international sample of people who use drugs: associations with other substance use and well-being. Drug Alcohol Depend. 2017;174:70–9.CrossRefPubMedGoogle Scholar
  38. 38.
    Zucconi S, Volpato C, Adinolfi F, Gandini E, Gentile E, Loi A et al. Gathering consumption data on specific consumer groups of energy drinks.[Internet]. Available from:
  39. 39.
    Oglesby LW, Amrani KA, Wynveen CJ, Gallucci AR. Do energy drink consumers study more? J Community Health. 2018;43(1):48–54.CrossRefPubMedGoogle Scholar
  40. 40.
    Rao N, Spiller HA, Hodges NL, Chounthirath T, Casavant MJ, Kamboj AK, et al. An increase in dietary supplement exposures reported to US poison control centers. J Med Toxicol. 2017;13(3):227–37.CrossRefPubMedPubMedCentralGoogle Scholar
  41. 41.
    SAMHSA. Update on Emergency Department visits involving energy drinks: a continuing public health concern. Drug Abus Warn Netw. 2013. Accessed on 5.15.2018 [Internet]. Available from:
  42. 42.
    Ludden AB, O’Brien EM, Beliefs PKE. Behaviors, and contexts of adolescent caffeine use: a focus group study. Subst Use Misuse. 2017;52(9):1207–18.CrossRefPubMedGoogle Scholar
  43. 43.
    Bashir D, Reed-Schrader E, Olympia RP, Brady J, Rivera R, Serra T, et al. Adverse effects associated with energy drink consumption in adolescents. Pediatr Emerg Care. 2016;32(11):751–5.Google Scholar
  44. 44.
    Bonar EE, Cunningham RM, Polshkova S, Chermack ST, Blow FC, Walton MA. Alcohol and energy drink use among adolescents seeking emergency department care. Addict Behav. 2015;43:11–7.CrossRefPubMedGoogle Scholar
  45. 45.
    Francis J, Martin K, Costa B, Christian H, Kaur S, Harray A, et al. Informing intervention strategies to reduce energy drink consumption in young people: findings from qualitative research. J Nutr Educ Behav 2017;49(9):724–733.e1.Google Scholar
  46. 46.
  47. 47.
  48. 48.
    Accessed on 5.15.2018. Available from:
  49. 49.
    Accessed on 5.15.2018 [Internet]. Available from:
  50. 50.
  51. 51.
    Goldfarb M, Tellier C, Thanassoulis G. Review of published cases of adverse cardiovascular events after ingestion of energy drinks. Am J Cardiol. 2014;113(1):168–72.CrossRefPubMedGoogle Scholar
  52. 52.
    Jacobson BH, Hester GM, Palmer TB, Williams K, Pope ZK, Sellers JH, et al. Effect of energy drink consumption on power and velocity of selected sport performance activities. J Strength Cond Res. 2018;32(6):1613–8.CrossRefPubMedGoogle Scholar
  53. 53.
    Nehlig A, Daval JL, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev17(2):139–70.Google Scholar
  54. 54.
    Wolk BJ, Ganetsky M, Babu KM. Toxicity of energy drinks. Curr Opin Pediatr. 2012;24(2):243–51.CrossRefPubMedGoogle Scholar
  55. 55.
    de Sanctis V, Soliman N, Soliman AT, Elsedfy H, Di Maio S, El Kholy M, et al. Caffeinated energy drink consumption among adolescents and potential health consequences associated with their use: a significant public health hazard. Acta Biomed. 2017;88(2):222–31.PubMedGoogle Scholar
  56. 56.
    Balogh A, Harder S, Vollandt R, Staib AH. Intra-individual variability of caffeine elimination in healthy subjects. Int J Clin Pharmacol Ther Toxicol. 1992;30(10):383–7.PubMedGoogle Scholar
  57. 57.
    Accessed on 5.15.2018 [Internet]. Available from:
  58. 58.
    Chaban R, Kornberger A, Branski N, Buschmann K, Stumpf N, Beiras-Fernandez A, et al. In-vitro examination of the positive inotropic effect of caffeine and taurine, the two most frequent active ingredients of energy drinks. BMC Cardiovasc Disord. 2017;17(1):1–8.CrossRefGoogle Scholar
  59. 59.
    • Souza DB, Del Coso J, Casonatto J, Polito MD. Acute effects of caffeine-containing energy drinks on physical performance: a systematic review and meta-analysis. Eur J Nutr. 2017;56(1):13–27. This systematic review analyzes the acute effects of caffeinated energy drinks on physical performance. Google Scholar
  60. 60.
    Xu Y-J, Arneja AS, Tappia PS, Dhalla NS. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57–65.PubMedPubMedCentralGoogle Scholar
  61. 61.
    Jeffries O, Hill J, Patterson SD, Waldron M. Energy drink doses of caffeine and taurine have a null or negative effect on sprint performance. J Strength Cond Res. 2017;1Google Scholar
  62. 62.
    Seifert SM, Seifert SA, Schaechter JL, Bronstein AC, Benson BE, Hershorin ER, et al. An analysis of energy-drink toxicity in the National Poison Data System. Clin Toxicol. 2013;51(7):566–74.CrossRefGoogle Scholar
  63. 63.
    Valle MTC, Couto-Pereira NS, Lampert C, Arcego DM, Toniazzo AP, Limberger RP, et al. Energy drinks and their component modulate attention, memory,and antioxidant defences in rats. Eur J Nutr. 2017;
  64. 64.
    Vivekanandarajah A, Ni S, Waked A. Acute hepatitis in a woman following excessive ingestion of an energy drink: a case report. J Med Case Rep. 2011;5:227.CrossRefPubMedPubMedCentralGoogle Scholar
  65. 65.
    Huang B, Kunkel D, Kabany M El. Acute liver failure following one year of daily consumption of a sugar-free energy drink. ACG Case Reports J 2014;1(4):214–216.Google Scholar
  66. 66.
    Harb JN, Taylor ZA, Khullar V, Sattari M. Rare cause of acute hepatitis: a common energy drink. BMJ Case Rep. 2016;2016:1–4.Google Scholar
  67. 67.
    Astorino TA, Matera AJ, Basinger J, Evans M, Schurman T, Marquez R. Effects of red bull energy drink on repeated sprint performance in women athletes. Amino Acids. 2012;42(5):1803–8.CrossRefPubMedGoogle Scholar
  68. 68.
    Del Coso J, Muñoz-Fernández VE, Muñoz G, Fernández-Elías VE, Ortega JF, Hamouti N, et al. Effects of a caffeine-containing energy drink on simulated soccer performance. PLoS One. 2012;7(2):e31380.CrossRefPubMedPubMedCentralGoogle Scholar
  69. 69.
    Salinero JJ, Lara B, Abian-Vicen J, Gonzalez-Mill NC, Areces F, Gallo-Salazar C, et al. The use of energy drinks in sport: perceived ergogenicity and side effects in male and female athletes. Br J Nutr. 2014;112(9):1494–502.CrossRefPubMedGoogle Scholar
  70. 70.
    Smit HJ, Cotton JR, Hughes SC, Rogers PJ. Mood and cognitive performance effects of “energy” drink constituents: caffeine, glucose and carbonation. Nutr Neurosci. 2004;7(3):127–39.CrossRefPubMedGoogle Scholar
  71. 71.
    • Ali F, Rehman H, Babayan Z, Stapleton D, Joshi DD. Energy drinks and their adverse health effects: a systematic review of the current evidence. Postgrad Med. 2015;127(3):308–22. This review highlights the adverse health effects of energy drinks. Google Scholar
  72. 72.
    Higgins JP, Babu K, Deuster PA, Shearer J. Energy drinks: a contemporary issues paper. Curr Sports Med Rep. 2018;17(2):65–72.CrossRefPubMedGoogle Scholar
  73. 73.
    Gunja N, Brown JA. Energy drinks: health risks and toxicity. Med J Aust. 2012;196(1):46–9.CrossRefPubMedGoogle Scholar
  74. 74.
    Marmorstein NR. Interactions between energy drink consumption and sleep problems: associations with alcohol use among young adolescents. J Caffeine Res. 2017;7(3):111–6.CrossRefPubMedPubMedCentralGoogle Scholar
  75. 75.
    Fletcher EA, Lacey CS, Aaron M, Kolasa M, Occiano A, Shah SA. Randomized controlled trial of high-volume energy drink versus caffeine consumption on ECG and hemodynamic parameters. J Am Heart Assoc. 2017;6(5):1–8.CrossRefGoogle Scholar
  76. 76.
    Gray B, Ingles J, Medi C, Driscoll T, Semsarian C. Cardiovascular effects of energy drinks in familial long QT syndrome: a randomized cross-over study. Int J Cardiol. 2017;231:150–4.CrossRefPubMedGoogle Scholar
  77. 77.
    Higgins JP, Yang B, Herrin NE, Yarlagadda S, Le GT, Ortiz BL, et al. Consumption of energy beverage is associated with attenuation of arterial endothelial flow-mediated dilatation. World J Cardiol. 2017;9(2):162.CrossRefPubMedPubMedCentralGoogle Scholar
  78. 78.
    Pagano CW, Wu M, Wu L. Acute visual loss and intraretinal hemorrhages associated to energy drink consumption. Int Ophthalmol. 2017;37(6):1349–51.CrossRefPubMedGoogle Scholar
  79. 79.
    Worthley MI, Prabhu A, De Sciscio P, Schultz C, Sanders P, Willoughby SR. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med. 2010;123(2):184–7.CrossRefPubMedGoogle Scholar
  80. 80.
    Williams RD, Housman JM, Odum M, Rivera AE. Energy drink use linked to high-sugar beverage intake and BMI among teens. Am J Health Behav. 2017;41(3):259–65.CrossRefPubMedGoogle Scholar
  81. 81.
    Richards G, Smith APA. Review of energy drinks and mental health, with a focus on stress, anxiety and Depression. J Caffeine Res. 2016;6(2):49–63.CrossRefPubMedPubMedCentralGoogle Scholar
  82. 82.
    Kim SY, Sim S, Choi HG. High stress, lack of sleep, low school performance, and suicide attempts are associated with high energy drink intake in adolescents. PLoS One. 2017;12(11):1–12.Google Scholar
  83. 83.
    Utter J, Denny S, Teevale T, Sheridan J. Energy drink consumption among New Zealand adolescents: associations with mental health, health risk behaviours and body size. J Paediatr Child Health. 2018;54(3):279–83.CrossRefPubMedGoogle Scholar
  84. 84.
    Jeffers AJ, Hill KEV, Benotsch EG. Energy drinks, weight loss and disordered eating behaviors. J Am Coll Heal. 2014;62(5):336–42.CrossRefGoogle Scholar
  85. 85.
    Arria AM, Caldeira KM, Bugbee BA, Vincent KB, O’Grady KE. Trajectories of energy drink consumption and subsequent drug use during young adulthood. Drug Alcohol Depend. 2017;179:424–32.CrossRefPubMedPubMedCentralGoogle Scholar
  86. 86.
    Picard-Masson M, Loslier J, Paquin P, Bertrand K. Consumption of energy drinks among Québec college students. Can J Public Health. 2017;107(6):e514–9.CrossRefPubMedGoogle Scholar
  87. 87.
    • Leal WE, Jackson DB. Energy drinks and escalation in drug use severity: An emergent hazard to adolescent health. Prev Med (Baltim). 2018;111:391–6. This study reviews the relationship between energy drinks consumption and drug use. Google Scholar
  88. 88.
    Polak K, Dillon P, Koch JR, Miller WG, Thacker L, Svikis D. Energy drink use is associated with alcohol and substance use in eighth, tenth, and twelfth graders. Prev Med Reports. 2016;4:381–4.CrossRefGoogle Scholar
  89. 89.
    Accessed on 5.15.2018 [Internet]. Available from:
  90. 90.
    Miyake ER, Marmorstein NR. Energy drink consumption and later alcohol use among early adolescents. Addict Behav. 2015;43:60–5.CrossRefPubMedGoogle Scholar
  91. 91.
    Holubcikova J, Kolarcik P, Madarasova Geckova A, Joppova E, van Dijk JP, Reijneveld SA. Young adolescents who combine alcohol and energy drinks have a higher risk of reporting negative behavioural outcomes. Int J Public Health. 2017;62(3):379–86.CrossRefPubMedGoogle Scholar
  92. 92.
    Berger L, Fendrich M, Fuhrmann D. Alcohol mixed with energy drinks: are there associated negative consequences beyond hazardous drinking in college students? Addict Behav. 2013;38(9):2428–32.CrossRefPubMedPubMedCentralGoogle Scholar
  93. 93.
    Howland J, Rohsenow DJ. Risks of energy drinks mixed with alcohol. JAMA - J Am Med Assoc. 2013;309(3):245–6.CrossRefGoogle Scholar
  94. 94.
    Accessed on 5.15.2018 [Internet]. Available from:
  95. 95.
    Accessed on 5.15.2018 [Internet]. Available from:
  96. 96.
    Marczinski CA, Fillmore MT, Maloney SF, Stamates AL. Faster self-paced rate of drinking for alcohol mixed with energy drinks versus alcohol alone. Psychol Addict Behav. 2017;31(2):154–61.CrossRefPubMedGoogle Scholar
  97. 97.
    Mosca A, Della Corte C, Sartorelli MR, Ferretti F, Nicita F, Vania A, et al. Beverage consumption and paediatric NAFLD. Eat Weight Disord. 2016;21(4):581–8.CrossRefPubMedGoogle Scholar
  98. 98.
    Reis R, Charehsaz M, Sipahi H, Ekici AID, Macit Ç, Akkaya H, et al. Energy drink induced lipid peroxidation and oxidative damage in rat liver and brain when used alone or combined with alcohol. J Food Sci. 2017;82(4):1037–43.CrossRefPubMedGoogle Scholar
  99. 99.
    McCrory C, White CM, Bowman C, Fenton N, Reid JL, Hammond D. Perceptions and Knowledge of caffeinated energy drinks: results of focus groups with Canadian youth. J Nutr Educ Behav 2017;49(4):304–311.e6.Google Scholar
  100. 100.
    Xiang N, Wethington H, Onufrak S, Belay B. Characteristics of US health care providers who counsel adolescents on sports and energy drink consumption. Int J Pediatr. 2014;2014:1–10.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Senthilkumar Sankararaman
    • 1
  • Wahid Syed
    • 2
  • Valentina Medici
    • 3
  • Thomas J. Sferra
    • 1
  1. 1.Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies & Children’s HospitalCase Western Reserve University School of MedicineClevelandUSA
  2. 2.Community Hospitalist Medical GroupClovis Community Medical CenterClovisUSA
  3. 3.Department of Internal Medicine (Division of Gastroenterology and Hepatology)University of California DavisSacramentoUSA

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