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Natural Products and Bioprospecting

, Volume 3, Issue 2, pp 52–55 | Cite as

New Lycopodium alkaloids from Lycopodium obscurum

  • Xue-Yuan Zhang
  • Liao-Bin Dong
  • Fei Liu
  • Xing-De Wu
  • Juan He
  • Li-Yan Peng
  • Huai-Rong Luo
  • Qin-Shi Zhao
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Regular Article
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Abstract

Three new Lycopodium alkaloids, obscurumines C-E (1–3), along with nine known compounds, were isolated from the club moss Lycopodium obscurum L. Structures of the new compounds were determined on the basis of their spectroscopic analysis and the relative configurations of 1 were established by X-ray crystallographic analysis. All the new isolates were tested for the acetylcholinesterase (AChE) inhibitory activity.
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Keywords

obscurumines Lydopodium alkaloids Lycopodium obscurum acetylcholinesterase (AChE) inhibitory activity 
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Copyright information

© The Author(s) 2013

This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  • Xue-Yuan Zhang
    • 1
    • 2
  • Liao-Bin Dong
    • 1
    • 2
  • Fei Liu
    • 1
    • 2
  • Xing-De Wu
    • 1
  • Juan He
    • 1
  • Li-Yan Peng
    • 1
  • Huai-Rong Luo
    • 1
  • Qin-Shi Zhao
    • 1
  1. 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of SciencesKunmingChina
  2. 2.University of Chinese Academy of SciencesBeijingChina

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