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The role of medicinal plants and natural products in melioration of cadmium toxicity

  • Sanjib Bhattacharya
Review
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Abstract

Cadmium is extremely toxic heavy metal and there is no specific, safe and efficacious therapeutic management of cadmium toxicity. Scientific literature reveals several medicinal plants and natural products alleviate experimentally induced cadmium toxicity in animals. The present review attempts to collate those experimental studies on medicinal plants and plant derived natural products with cadmium toxicity ameliorative effects. Literature survey was carried out by using internet and the studies for the last two decades were considered. Minerals and semi-synthetic or synthetic analogs of natural products were excluded. Literature study revealed that 36 medicinal plants and 16 natural products exhibited significant protection from cadmium toxicity in experimental animal models i.e., pre-clinical studies. Clinical studies were not found in literature. Relevant research in this field could lead to development of a potentially useful agent in therapeutic management of cadmium toxicity in humans.

Keywords

Cadmium Ascorbic acid Natural products Oxidative stress Quercetin 

Notes

Compliance with ethical standards

Ethical statement

N/A.

Conflict of interest

This manuscript described has not been published before; not under consideration for publication anywhere else; and has been approved by all co-authors.

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Copyright information

© Institute of Korean Medicine, Kyung Hee University and Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.West Bengal Medical Services Corporation Ltd.Salt Lake City, KolkataIndia

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