Oriental Pharmacy and Experimental Medicine

, Volume 13, Issue 2, pp 159–164 | Cite as

Central depressant activity of ethanol extract of Nymphaea alba rhizome in mice

  • Anindya BoseEmail author
  • Sarbani Dey Ray
  • Moumita Sahoo
Research Article


Ethanol extract of the of rhizome of Nymphaea alba, at graded doses was investigated for the central depressant activity of the ethanol extract of rhizome. The behavioral effect of the extract (75, 150 and 300 mg/kg) was evaluated using diazepam induced sleep test, hole-board test, beam walking assay, staircase test, open field test and elevated plus maze assay, all in mice. The findings of this study suggest that the extract of N. alba rhizome contains some bioactive principles that are sedative in nature.


Ethanol Central Depressant Sedative Rhizome 


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Copyright information

© Institute of Oriental Medicine, Kyung Hee University 2013

Authors and Affiliations

  1. 1.Division of Pharmaceutical ChemistryDr. B C Roy College of Pharmacy & Allied Health SciencesBidhannagarIndia
  2. 2.Institute of Pharmacy and Technology, SalipurCuttackIndia

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