Effect of Psoralea corylifolia Linn in sexual erectile dysfunction in diabetic rats

  • Prashant M. Tayade
  • M. J. N. Chandrasekar
  • S. N. Borde
  • Abhay S. Joshi
  • S. S. Angadi
  • S. J. Devdhe
Article
  • 332 Downloads

Abstract

Psoralea corylifolia Linn were used traditionally in Ayurveda for the treatment of male sexual dysfunction. The extract was administered (100 and 200 mg/kg, p.o.) to different groups of male rats. The female rats involved in mating were made receptive by hormonal treatment. The orientational activity, body weight, haematoogical parameters were studied and compared with the standard reference drug Yohimbine. Psoralea corylifolia produced significant aphrodisiac activity when compared to Diabetic Control and Normal Control. Psoralea corylifolia Linn showed a significant increase in number of licking, number of anogenital sniffing towards female and number of genital grooming towards self. Whereas significant decrease in number of climbing and nongenital grooming towards self was observed during all time observation in animals treated for 14 days and observation on one day, seven day and fourteen days treatment.

Keywords

Psoralea corylifolia Linn Aphrodisiac Streptozotocin Diabetes 

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Copyright information

© Institute of Oriental Medicine, Kyung Hee University 2013

Authors and Affiliations

  • Prashant M. Tayade
    • 1
  • M. J. N. Chandrasekar
    • 2
  • S. N. Borde
    • 3
  • Abhay S. Joshi
    • 1
  • S. S. Angadi
    • 1
  • S. J. Devdhe
    • 1
  1. 1.Yash Institute of PharmacyAurangabadIndia
  2. 2.J.S.S. College of PharmacyTamil NaduIndia
  3. 3.Department of ZoologyAurangabadIndia

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