Setaria genome sequencing: an overview

  • Charu Lata
  • Manoj PrasadEmail author


The genus Setaria includes two important C4 Panicoid grass species, namely S. italica (cultivated) and S. viridis (weed; wild ancestor), which together represent an appropriate model system for architectural, physiological, evolutionary, and genomic studies in related grasses. It is a diploid, inbreeder, self-fertile annual cereal grass having short life cycle and minimal growth requirements. There close relatedness to biofuel crops like switch grass and napier grass further signifies their importance. Further, foxtail millet is an important food and fodder grain crop grown in arid and semi-arid regions in many parts of the world. Therefore, an increasing interest in these species has led to a gradual accumulation and development of genomic data and genetic resources. Setaria genome sequencing is an outcome of such endeavors. These sequencing efforts uncovered several distinctive attributes of Setaria genome that may help in understanding its physiology, evolution and adaptation. This will not only aid in comparative genomics studies of Setaria and related crops including bioenergy grasses but also help in rapid advancements of genomics information for developing varieties with superior traits either through marker-assisted selection (MAS) or using transgenic approaches in these crops.


Biofuel Crop improvement Millets Marker-aided breeding Setaria Single nucleotide polymorphism 



Beijing Genome Initiative


United States Department of Energy-Joint Genome Initiative


Single Nucleotide Polymorphism


Transposable elements




Expressed-sequence tags


Long terminal repeats


Long Interspersed Nuclear Elements



This study was supported by the core grant from National Institute of Plant Genome Research and Department of Science & Technology (DST), Govt. of India. Charu Lata acknowledges DST, Govt. of India, New Delhi for the INSPIRE Faculty Award (Grant No.IFA-11LSPA-01).


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Copyright information

© Society for Plant Biochemistry and Biotechnology 2013

Authors and Affiliations

  1. 1.National Institute of Plant Genome Research (NIPGR)New DelhiIndia
  2. 2.National Research Centre on Plant BiotechnologyNew DelhiIndia

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