Mechanical properties and cytotoxicity of PLA/PCL films
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Thermodynamically immiscible poly(lactic acid) (PLA) and poly(ε-caprolactone) (PCL) were blended and solution-cast by adding the 3% compatibilizer (tributyl citrate, TBC) of the PCL weight. In the PLA/PCL composition range of 99/1–95/5 wt%, mechanical properties of the PLA/PCL films with TBC were always superior to those of the films without TBC. The tensile strength of 42.9 ± 3.5 MPa and the elongation at break of 10.3 ± 2.7% were observed for the 93/7 PLA/PCL films without TBC, indicating that PCL addition is effective for strength and ductility. However, the tensile strength of 54.1 ± 3.4 MPa and the elongation at break of 8.8 ± 1.8% were found for the 95/5 PLA/PCL with TBC, indicating that the effect of co-addition of PCL and TBC on mechanical properties of the films is more pronounced. No cytotoxicity was observed for the PLA/PCL films regardless of TBC addition.
KeywordsPoly(lactic acid) Poly(ε-caprolactone) Compatibilizer Tensile strength Cytotoxicity Cell proliferation
KJK and TH would like to acknowledge this material is based upon work supported in part by the National Science Foundation under Grant No. IIA-1301726.
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Conflict of interest
The authors declares there is no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
- 6.Seol B, Shin J, Oh G, Lee DY, Lee M. Characteristics of PU/PEG hybrid scaffolds prepared by electrospinning. J Biomed Eng Res. 2017;38:248.Google Scholar