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Duration of type 2 diabetes mellitus and pulmonary function tests: a correlative study

  • Swati Mittal
  • Manisha JindalEmail author
  • Saurabh Srivastava
  • Arun Garg
Original Article
  • 2 Downloads

Abstract

Background

Diabetes mellitus (DM) encompasses a group of metabolic disorders characterized by elevated levels of plasma glucose leading to macro- and micro-vascular damages to target organs. According to IDF, India had 73 million population of diabetes in 2017, and this figure may rise to 134 million adults by 2045 International Diabetes Federation, 2017. Since the alveolar capillary network in the lung is a large micro-vascular unit, microangiopathy may be targeting lungs along with other organs.

Objective

To correlate pulmonary function tests with duration of type 2 diabetes mellitus.

Method

The cross-sectional study was conducted on one hundred six patients of type 2 diabetes mellitus who met the inclusion and exclusion criteria. Diabetic cases were categorized on the basis of duration of disease. RMS Helios 401 computerized spirometer was used to assess pulmonary functions. Statistical tests employed include t test, ANOVA, and correlation coefficient analysis.

Result

The mean duration of disease for patients with diabetes was 10.17 ± 5.16 year. There was a significant negative correlation between the parameters of lung function test (p value < 0.05) with duration of diabetes.

Conclusion

We found that pulmonary functions have inverse relationship with increase in duration of type 2 diabetes mellitus.

Keywords

Diabetes mellitus Pulmonary function test Forced vital capacity Forced expiratory volume in first second 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Research Society for Study of Diabetes in India 2019

Authors and Affiliations

  • Swati Mittal
    • 1
  • Manisha Jindal
    • 1
    Email author
  • Saurabh Srivastava
    • 2
  • Arun Garg
    • 3
  1. 1.Department of Physiology, SMS&RSharda UniversityGreater NoidaIndia
  2. 2.Department of MedicineGovernment Institute of Medical SciencesGreater NoidaIndia
  3. 3.St Joseph’s HospitalGhaziabadIndia

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