Journal of NeuroVirology

, Volume 25, Issue 1, pp 137–140 | Cite as

Recurrent strokes, central nervous system vasculitis, and acquired protein S deficiency secondary to varicella zoster in a child with AIDS

  • Jake A. Deviley
  • Darby Oldenburg
  • Laurence C. Berg
  • William A. AggerEmail author
Case Report


A child with vertical transmission of human immunodeficiency virus refractory to therapy developed zoster-induced protein S deficiency and recurrent strokes. Extensive carotid arteritis was found postmortem. The carotid tissue was positive for herpes varicella zoster by polymerase chain reaction, as were immunofixation stains of the arterial wall.


Zoster AIDS Arteritis Protein S Strokes 



The authors would like to thank Steven Lovrich, Ph.D., Gundersen Health System; Scott Cooper, Ph.D., University of Wisconsin – La Crosse; and Bernadette Taylor, Ph.D., University of Wisconsin – La Crosse.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Journal of NeuroVirology, Inc. 2018

Authors and Affiliations

  • Jake A. Deviley
    • 1
  • Darby Oldenburg
    • 1
  • Laurence C. Berg
    • 2
  • William A. Agger
    • 1
    • 3
    Email author
  1. 1.Department of Medical ResearchGundersen Health SystemLa CrosseUSA
  2. 2.Department of PathologyGundersen Health SystemLa CrosseUSA
  3. 3.Department of Infectious DiseaseGundersen Health SystemLa CrosseUSA

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