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Journal of NeuroVirology

, Volume 22, Issue 5, pp 695–698 | Cite as

Epstein-Barr virus hemorrhagic meningoencephalitis: case report and review of the literature

  • Bianca Branco AscençãoEmail author
  • Ana Catarina Gonçalves
  • Nuno Luís
  • Joana Sá
  • Ana Paula Brito
  • José Manuel Poças
Case Report

Abstract

Neurologic complications related to Epstein-Barr virus (EBV) in immunocompetent adults are rare and most commonly self-limited. However, severe cases have been previously reported in the literature. We describe a case of meningoencephalitis with frontal bilateral hemorrhage in a non-immunocompromised adult following an EBV infection of the central nervous system confirmed by the presence of EBV-DNA in the cerebrospinal fluid. During the patient’s hospital stay, there was a favorable clinical and radiologic evolution and the patient was discharged asymptomatic. To our knowledge, this is the fourth case of hemorrhagic meningoencephalitis related to EBV and the first one in an immunocompetent patient with a favorable outcome.

Keywords

Meningoencephalitis EBV Hemorrhage 

Notes

Compliance with ethical standards

Funding

None.

Conflict of interest

None declared.

Ethical approval

Not required.

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Copyright information

© Journal of NeuroVirology, Inc. 2016

Authors and Affiliations

  • Bianca Branco Ascenção
    • 1
    Email author
  • Ana Catarina Gonçalves
    • 1
  • Nuno Luís
    • 1
  • Joana Sá
    • 1
  • Ana Paula Brito
    • 1
  • José Manuel Poças
    • 1
  1. 1.Centro Hospitalar de SetúbalSetubalPortugal

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