The selective constraints of ecological specialization in mustelidae on mitochondrial genomes
- 40 Downloads
The locomotor preference may drive the evolution of animals in a certain way, and species living in different environments might own different energy requirement style. We hypothesized that the locomotor preference and habitat variation might impose different influence on mustelidae mitochondrial genomes (mtDNA). To test this, we sampled 22 species of mustelidae, encompassing natatorial, scansorial, fossorial, and non-specialists, to determine whether the variation in locomotor specialization influence the evolution of their mitochondrial genomes. The selective constraints analyses showed that the ratio of non-synonymous/synonymous substitutions (dN/dS) in mitochondrial protein-coding genes (PCGs) was significantly higher in non-specialist group than specialist groups (natatorial, scansorial, and fossorial), which suggested that the specialist groups’ mtDNA experienced much stronger purifying selection during evolution as they need much more energy in their daily life. When comparing dN/dS of each PCG among these four groups, six protein-coding genes (ND2-3, ND5, CoxIII, ATP6, Cytb) also showed different dN/dS ratios between non-specialist and specialist groups. We also found that the ATP8 gene was positively selected in the branch of Lutra lutra. Our study thus demonstrated that the selective constraints relevant to locomotor specialization play an essential role in the evolution of mustelidae mtDNA.
KeywordsLocomotor preference Mitochondrial genomes Mustelidae Selective constraints dN/dS
This work was financially supported by the Special Fund for Forest Scientific Research in the Public Welfare (201404420) and the National Natural Science Foundation of China (31672313, 31372220).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- Edgar RC (2004) MUSCLE: multiple sequence alignment with improved accuracy and speed. In: Computational Systems Bioinformatics Conference.Google Scholar
- Holmes T (1980) Locomotor adaptations in the limb skeletons of North American mustelids. Humboldt State UniversityGoogle Scholar
- Proulx G, Aubry K, Birks J, Buskirk S, Fortin C, Frost H, Krohn W, Mayo L, Monakhov V, Payer D 2005. World distribution and status of the genus Martes in 2000Google Scholar
- Williams TM (1983) Locomotion in the north American mink, a semi-aquatic mammal. II The effect of an elongate body on running energetics and gait patterns. J Exp Biol 103:283–295Google Scholar
- Zhang S, Han J, Zhong D, Wang T (2013) Analysis of selective constraints on mitochondrial DNA, flight ability and physiological index on avian. IEEE Eng Med Biol 35:1498–1501Google Scholar