Fast Eruption Desorption Ionization for Mass Spectrometric Analysis
Fast eruption desorption ionization (FEDI) technique was developed for simple, rapid, and sensitive analysis of various compounds. The FEDI allows three analytical modes each with the unique characteristic. The results demonstrated that non-assisted eruption was suitable for stable and volatile compounds, energetic material (EM)-assisted for nonvolatile molecules especially metal compounds, and solvent-assisted eruption for fragile molecules. High-quality mass spectra with intact ions of analytes were obtained in positive and negative ion modes.
KeywordsMass spectrometry Fast eruption desorption ionization Non-assisted eruption EM-assisted eruption Solvent-assisted eruption
The authors are grateful for the financial supports from the National Key Research and Development Program of China (No. 2016YFC0800704) and the National Science Foundation of China (21532005, 21772227, and 21472228).