Journal of The American Society for Mass Spectrometry

, Volume 25, Issue 9, pp 1515–1520 | Cite as

Direct Analysis of Large Living Organism by Megavolt Electrostatic Ionization Mass Spectrometry

  • Kwan-Ming Ng
  • Ho-Wai Tang
  • Sin-Heng Man
  • Pui-Yuk Mak
  • Yi-Ching Choi
  • Melody Yee-Man Wong
Research Article


A new ambient ionization method allowing the direct chemical analysis of living human body by mass spectrometry (MS) was developed. This MS method, namely Megavolt Electrostatic Ionization Mass Spectrometry, is based on electrostatic charging of a living individual to megavolt (MV) potential, illicit drugs, and explosives on skin/glove, flammable solvent on cloth/tissue paper, and volatile food substances in breath were readily ionized and detected by a mass spectrometer.

Key words

Megavolt electrostatic ionization Large living organism Direct analysis Mass spectrometry 

Supplementary material

13361_2014_932_MOESM1_ESM.docx (741 kb)
ESM 1(DOCX 741 KB)


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Copyright information

© American Society for Mass Spectrometry 2014

Authors and Affiliations

  • Kwan-Ming Ng
    • 1
  • Ho-Wai Tang
    • 1
  • Sin-Heng Man
    • 1
  • Pui-Yuk Mak
    • 1
  • Yi-Ching Choi
    • 1
  • Melody Yee-Man Wong
    • 1
  1. 1.Department of Chemistry and State Key Laboratory of Synthetic ChemistryThe University of Hong KongHong KongPeople’s Republic of China

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