Novel Galvanic Nanostructures of Ag and Pd for Efficient Laser Desorption/Ionization of Low Molecular Weight Compounds

  • Yuliya E. Silina
  • Florian Meier
  • Valeriy A. Nebolsin
  • Marcus Koch
  • Dietrich A. Volmer
Research Article
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Abstract

A simple approach for synthesis of palladium and silver nanostructures with readily adjustable morphologies was developed using galvanic electrochemical deposition, for application to surface-assisted laser desorption/ionization (SALDI) of small biological molecules. A range of fatty acids, triglycerides, carbohydrates, and antibiotics were investigated to assess the performance of the new materials. Intense analyte cations were generated from the galvanic surfaces upon UV laser irradiation such as potassium adducts for a film thickness <100 nm (originating from impurities of the electrolyte solution) and Pd and Ag cluster ions for films with a thickness >120 nm. Possible laser desorption/ionization mechanisms of these galvanic structures are discussed. The films exhibited self-organizing abilities and adjustable morphologies by changing electrochemical parameters. They did not require any stabilizing agents and were inexpensive and very easy to produce. SALDI analysis showed that the materials were stable under ambient conditions and analytical results with excellent measurement reproducibility and detection sensitivity similar to MALDI were obtained. Finally, we applied the galvanic surfaces to fast screening of natural oils with minimum sample preparation.

Figure

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Key words

Surface-assisted laser desorption/ionization MALDI Galvanic films Nanoparticles Silver films Palladium films Low molecular weight compounds Small molecules 
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Notes

Acknowledgments

D.A.V. acknowledges research support by the Alfried Krupp von Bohlen und Halbach-Stiftung. The authors thank Rolf Hempelmann and Martin Weinmann (Saarland University, Saarbrücken) for access to the electrochemical equipment.

Supplementary material

13361_2014_853_MOESM1_ESM.docx (4.6 mb)
ESM 1 (DOCX 4673 kb)

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Copyright information

© American Society for Mass Spectrometry 2014

Authors and Affiliations

  • Yuliya E. Silina
    • 1
  • Florian Meier
    • 1
  • Valeriy A. Nebolsin
    • 2
  • Marcus Koch
    • 3
  • Dietrich A. Volmer
    • 1
  1. 1.Institute of Bioanalytical ChemistrySaarland UniversitySaarbrückenGermany
  2. 2.Department of Physical ChemistryVoronezh State Technical UniversityVoronezhRussia
  3. 3.Leibniz Institute for New Materials (INM)SaarbrückenGermany

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