Evaluation of the Potential of GC-APCI-MS for the Analysis of Pesticide Residues in Fatty Matrices

  • María Luz Gómez-Pérez
  • Patricia Plaza-Bolaños
  • Roberto Romero-González
  • José Luis Martínez Vidal
  • Antonia Garrido Frenich
Application Note
First Online:
Received:
Revised:
Accepted:

Abstract

A method based on gas chromatography-atmospheric pressure chemical ionization-mass spectrometry (GC-APCI-MS) has been developed for the analysis of pesticides in meat by using quadrupole-time of flight mass spectrometry (QTOF-MS). Ionization and MS conditions were studied for 71 compounds, although only 51 showed acceptable performance. The protonated form of the analytes was mainly found ([M + H]+), although some compounds generated the molecular ion (M+•). A fast and generic extraction procedure was applied in sample pretreatment. The analytical method was suitable for qualitative analysis, and it was also evaluated for quantitative analysis, obtaining adequate recovery and precision values for most of the studied analytes at two concentration levels (50 and 150 μg/kg). Several operational drawbacks were found with this instrument, such as slow stabilization and moderate sensitivity, although the fast switching between LC and GC allows the increase of its applicability.

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Keywords

GC-APCI Ionization process Pesticides Generic extraction Meat 
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Notes

Acknowledgments

The authors gratefully acknowledge the Spanish Ministry of Economy and Competitiveness (MINECO) and FEDER for financial support (Project Ref. AGL2010-21370). M.L.G.P. acknowledges her grant (FPI) (MINECO, Ref. AGL 2010-21370). P.P.B. is grateful for personal funding through the Agrifood Campus of International Excellence, ceiA3 (Spanish Ministry of Education, Culture, and Sport). R.R.G. is also grateful for personal funding through the Ramón y Cajal Program (MINECO-ESF).

Supplementary material

13361_2014_849_MOESM1_ESM.doc (465 kb)
ESM 1 (DOC 465 kb)

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Copyright information

© American Society for Mass Spectrometry 2014

Authors and Affiliations

  • María Luz Gómez-Pérez
    • 1
  • Patricia Plaza-Bolaños
    • 1
  • Roberto Romero-González
    • 1
  • José Luis Martínez Vidal
    • 1
  • Antonia Garrido Frenich
    • 1
  1. 1.Analytical Chemistry of Contaminants, Department of Chemistry and Physics, Research Centre for Agricultural and Food Biotechnology (BITAL)University of AlmeríaAlmeríaSpain

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