Locally made ready-to-use therapeutic food for treatment of malnutrition: A randomized controlled trial
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- Singh, A.S., Kang, G., Ramachandran, A. et al. Indian Pediatr (2010) 47: 679. doi:10.1007/s13312-010-0100-8
To evaluate the effectiveness of a locally made ready-to-use therapeutic food (RUTF) in decreasing mild to moderate malnutrition.
A randomized open label, controlled trial.
Pre-schools run by the Department of Community Health in Kaniyambadi administrative block, Vellore, India; duration of follow-up - 3 months from the date of recruitment.
Pupils aged 18–60 months with Weight-for-Age ≤2 SD.
A locally produced energy-dense supplement (RUTF), and the current standard of care [teaching caregivers how to make a fortified cereal-milk supplement called High Calorie Cereal Milk (HCCM)].
Main outcome measures
Increase in weight-for-age status; increase in levels of plasma zinc, vitamin B12, serum albumin and haemoglobin.
The Mean (SD) weight gain at 3 months was higher in the RUTF group: RUTF (n=51): 0.54 kg; (SE = 0.05; 95% CI = 0.44–0.65) vs HCCM (n=45): 0.38 kg; (SE = 0.06; 95% CI = 0.25–0.51), P = 0.047. The weight gain per kilogram of body weight was directly proportional to the severity of malnutrition.
Community-based treatment showed weight gain in both groups, the gain being higher with RUTF.
Key wordsIndia Indigenous Management Malnutrition Nutrition therapy
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