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Neurotherapeutics

, Volume 11, Issue 3, pp 543–552 | Cite as

Spinal Stimulation for Movement Disorders

  • Claire Thiriez
  • Jean-Marc Gurruchaga
  • Colette Goujon
  • Gilles Fénelon
  • Stéphane Palfi
Review

Abstract

Epidural spinal cord stimulation (SCS) is currently proposed to treat intractable neuropathic pain. Since the 1970s, isolated cases and small cohorts of patients suffering from dystonia, tremor, painful leg and moving toes (PLMT), or Parkinson’s disease were also treated with SCS in the context of exploratory clinical studies. Despite the safety profile of SCS observed in these various types of movement disorders, the degree of improvement of abnormal movements following SCS has been heterogeneous among patients and across centers in open-label trials, stressing the need for larger, randomized, double-blind studies. This article provides a comprehensive review of both experimental and clinical studies of SCS application in movement disorders.

Key Words

Spinal cord stimulation Parkinson’s disease dystonia painful leg and moving toes tremor neuropathic pain 

Notes

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Supplementary material

13311_2014_291_MOESM1_ESM.pdf (1.2 mb)
ESM 1 (PDF 1.19 MB)
13311_2014_291_MOESM2_ESM.pdf (1.2 mb)
ESM 2 (PDF 1.19 MB)

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Copyright information

© The American Society for Experimental NeuroTherapeutics, Inc. 2014

Authors and Affiliations

  1. 1.AP-HP, Department of NeurologyCréteilFrance
  2. 2.Department of NeurosurgeryGroupe Hospitalier Henri MondorCréteilFrance
  3. 3.Université Paris Est-CréteilFaculté de MédecineCréteilFrance

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