Vacuum-assisted wound closure and liver transplantation: new perspective and challenges
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To the editor,
Deep and superficial surgical site infections (SSIs) are commonly diagnosed after liver transplantation (LT). Liver transplanted patients are peculiarly susceptible to infections due to their pre-LT disease and post-LT immunosuppression . For this reason, SSIs are burdened by poorer post-LT results and increased LT-related costs . Different strategies were explored to reduce SSIs incidence and their systemic complications.
Magistri et al.  recently published a paper that describes their series of negative pressure wound treatment (NPWT) in LT patients. The study reports three cases of deep and ten of superficial SSIs treated with NPWT over a 17-year period. They applied NPWT after wound infection, delayed wound healing, abdominal sepsis or compartment syndrome within a maximum duration of 3 weeks. Mean NPWT duration for superficial SSIs was 13.9 (3–21) days and 9.3 (8–10) days in deep SSI, while hospital stay was 42.6 (8–80) days and 62 (23–133) days,...
KeywordsVacuum-assisted wound closure Liver transplantation Surgical site infections Multidrug resistant
Compliance with ethical standards
Conflict of interest
All authors declare that they have no conflicts of interest.
Research involving human participants and/or animals
The study, involving human participants, have been performed in accordance with the ethical standards of the Declaration of Helsinki and its later amendments. our institutional Ethical committee was informed about the study and the patients
All patient's signed an informed consent.
- 4.Dondossola D, Cavenago MSP, Antonelli B et al (2015) Negative pressure wound treatment of infections caused by extensively drug-resistant gram-negative bacteria after liver transplantation: two case reports. Transplant Proc 47(7):2145–2149. https://doi.org/10.1016/j.transproceed.2014.11.078 CrossRefPubMedGoogle Scholar