Updates in Surgery

, Volume 70, Issue 2, pp 265–271 | Cite as

Prognostic factors for short-term and long-term outcomes of gastric cancer surgery for elderly patients: 10 years of experience at a single tertiary care center

  • Stefano de Pascale
  • Daniele Belotti
  • Andrea CelottiEmail author
  • Eleonora Maddalena Minerva
  • Vittorio Quagliuolo
  • Riccardio Rosati
  • Uberto Fumagalli Romario
Original Article
Part of the following topical collections:
  1. Gastric Cancer Surgery


This retrospective study aimed to verify the short-term and long-term outcomes of elderly patients who underwent gastric resection for gastric cancer and to compare the results between younger and elderly patients. 222 Patients, who underwent gastrectomy between January 2005 and December 2014, were divided into 2 groups: ≤ 75 years old (group A) and > 75 years (group B). The groups were homogeneous except for more advanced pathological stage (p = 0.011) and higher number of comorbidities in group B (p < 0.001) and a higher rate of neoadjuvant or adjuvant complementary therapy in group A (p = 0.029 and p < 0.001). Perioperative morbidity rates were 38.7 and 65.5% (p = 0.001), and mortality rates were 2.5 and 7.9% (p = ns), respectively. The independent negative prognostic factors for morbidity were age older than 75 years [odds ratio (OR) 2.7], multiple organ resection (OR 2.4), and male gender (OR 1.8). The 36-month survival rates were 76.1% and 42.1% (p = 0.002) and disease-free survival rates were 85% and 76.3% (p = 0.017), respectively. Surgical indications should not be limited by age.


Comorbid disease Gastric cancer Malignant disease Elderly 


Compliance with ethical standards

Conflict of interest

All authors declare no conflict of interest or financial support.

Research involving human participants and/or animals

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

For this type of study formal consent is not required.


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Copyright information

© Italian Society of Surgery (SIC) 2018

Authors and Affiliations

  • Stefano de Pascale
    • 1
  • Daniele Belotti
    • 2
  • Andrea Celotti
    • 1
    • 5
    Email author return OK on get
  • Eleonora Maddalena Minerva
    • 3
  • Vittorio Quagliuolo
    • 3
  • Riccardio Rosati
    • 4
  • Uberto Fumagalli Romario
    • 1
  1. 1.General Surgery, ASST Spedali Civili BresciaBresciaItaly
  2. 2.General Surgery, ASST Fatebenefrattelli SaccoMilanItaly
  3. 3.General and Oncologic Surgery, Humanitas Research HospitalRozzanoItaly
  4. 4.General and Gastro-enteric Surgery University Vita e Salute San RaffaeleMilanItaly
  5. 5.II Surgery, Spedali Civili di BresciaBresciaItaly

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