Updates in Surgery

, Volume 68, Issue 1, pp 59–62 | Cite as

Laparoscopic resection for T4 colon cancer: perioperative and long-term outcomes

  • Frederic BretagnolEmail author
  • Joel Leroy
Review Article
Part of the following topical collections:
  1. Mini Invasive Colorectal Surgery


Laparoscopic resection has been considered a contraindication for T4 colorectal cancer. It is argued that it is a challenging and demanding procedure with high conversion rate, inadequate oncologic clearance and surgical outcomes. There are only a few data on short- and long-term operative results. This review aimed at assessing feasibility and operative and oncologic results of laparoscopic resection for T4 colorectal cancer.


Colorectal cancer T4 tumor Laparoscopy 


Compliance with ethical standards

Conflict of interest

The Authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in the study involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Research involving human participants and/or animals

This articles does not contain any studies with human participants or animal performed by any of the authors.

Informed consent

For this type of study formal consent is not required.


  1. 1.
    Fleming ID, Cooper JS, Henson DE, et al (1998) In: AJCC Cancer Staging Handbook. Lippincott-Raven, Philadelphia, p 10Google Scholar
  2. 2.
    Amshel C, Avital S, Miller A, Sands L, Marchetti F, Hellinger M (2005) T4 rectal cancer: analysis of patients outcome after surgical excision. Am Surg 971:901–904Google Scholar
  3. 3.
    Nakafusa Y, Tanaka T, Tanaka M, Kitajima Y, Sato S, Miyazaki K (2004) Comparison of multivisceral resection and standard operation for locally advanced colorectal cancer: analysis of prognostic factors for short-term and long-term outcome. Dis Colon Rectum 47:2055–2063CrossRefPubMedGoogle Scholar
  4. 4.
    Veldkamp R, Gholghesaei M, Bonjer HJ et al (2004) Laparoscopic resection of colon cancer: consensus of the European Association of Endoscopic Surgery (EAES). Surg Endosc 18:1163–1185CrossRefPubMedGoogle Scholar
  5. 5.
    Bretagnol F, Dedieu A, Zappa M, Guedj N, Ferron M, Panis Y (2011) T4 colorectal cancer: is laparoscopic resection contraindicated? Colorectal Dis 13:138–143CrossRefPubMedGoogle Scholar
  6. 6.
    Veldkamp R, Kuhry E, Hop WC et al (2005) Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol 6:477–484CrossRefPubMedGoogle Scholar
  7. 7.
    Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AM, Heath RM, Brown JM (2007) Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol 25:3061–3068CrossRefPubMedGoogle Scholar
  8. 8.
    Buunen M, Veldkamp R, Hop WC et al (2009) Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 10:44–52CrossRefPubMedGoogle Scholar
  9. 9.
    Kim IY, Kim BR, Kim YW (2015) The short-term and oncologic outcomes of laparoscopic versus open surgery for T4 colon cancer. Surg Endosc 2015 (In press)Google Scholar
  10. 10.
    Elnahas A, Sunil S, Jackson TD, Okrainec A (2015) Laparoscopic versus open surgery for T4 colon cancer: evaluation of margin status. Surg Endosc (In press)Google Scholar
  11. 11.
    Shukla PJ, Trencheva K, Merchant C, Maggiori L, Michelassi F, Sonoda T, Lee SW, Milsom JW (2015) Laparoscopic resection of T4 colon cancers: is it feasible? Dis Colon Rectum 58:25–31CrossRefPubMedGoogle Scholar
  12. 12.
    Yamamoto S, Inomata M, Katayama H, Mizusawa J, Etoh T, Konishi F et al (2014) Short-term surgical outcomes from a randomized controlled trial to evaluate laparoscopic and open D3 dissection for stage II/III colon cancer. Ann Surg 260:23–30CrossRefPubMedGoogle Scholar
  13. 13.
    Laurent C, Leblanc F, Gineste C, Saric J, Rullier E (2007) Laparoscopic approach in surgical treatment of rectal cancer. Br J Surg 94:1555–1561CrossRefPubMedGoogle Scholar
  14. 14.
    Thorpe H, Jayne DG, Guillou PJ, Quirke P, Copeland J, Brown JM (2008) Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer. Br J Surg 95:199–205CrossRefPubMedGoogle Scholar
  15. 15.
    Lehnert T, Methner M, Pollok A, Schainle A, Hinz U, Herfarth C (2002) Multivisceral resection for locally advanced primary colon and rectal cancer. Ann Surg 235:217–225CrossRefPubMedPubMedCentralGoogle Scholar
  16. 16.
    Valentini V, Coco C, Rizzi G et al (2009) Outcomes of clinical T4M0 extra-peritoneal rectal cancer treated with preoperative radiochemotherapy and surgery: a prospective evaluation of a single institutional experience. Surgery 145:486–494CrossRefPubMedGoogle Scholar
  17. 17.
    Ishiguro S, Akasu T, Fujita S, Yamamoto S, Kusters M, Moriya Y (2009) Pelvic exenteration for clinical T4 rectal cancer: oncologic outcome in 93 patients at a single institution over a 30-year period. Surgery 145:189–195CrossRefPubMedGoogle Scholar

Copyright information

© Italian Society of Surgery (SIC) 2016

Authors and Affiliations

  1. 1.Department of Digestive SurgeryLouis Mourier University Hospital (APHP)ColombesFrance
  2. 2.Department of Digestive and Endocrine Surgery, Nouvel Hôpital CivilHôpitaux Universitaires de StrasbourgStrasbourgFrance
  3. 3.Research Institute Against Cancer/European Institute of Telesurgery (IRCAD/EITS)StrasbourgFrance

Personalised recommendations