Tumor Biology

, Volume 34, Issue 4, pp 2379–2382 | Cite as

Is breast cancer in young Asian women more aggressive than in Caucasians? A cross-sectional analysis

  • Muy-Kheng M. TeaEmail author
  • Lei Fan
  • James W. Delancey
  • Christine Staudigl
  • Stefan Steurer
  • Christina Lang
  • Zhi-Ming Shao
  • Christian F. Singer
Research Article


Ethnic differences in breast cancer are well described in studies comparing Hispanic and African-American populations to Caucasian populations. The aim of this study was to analyze the biological characteristics of breast cancer (BC) in the young Asian/Han Chinese population compared to Caucasians/Central Europeans. Histopathologies of 642 invasive BC in women at the age of 40 years and younger were analyzed in China and Austria. Pearson’s chi-squared test was used to assess differences in the analyzed populations. Significantly larger BC >2 cm (p < 0.0001) and poorly differentiated BC (p = 0.02) as well as more triple-negative BC (p = 0.002) were identified among the Han Chinese group compared to the Central European group. This analysis will provide ethnic-specific insight into the biological characteristics of BC in young patients worldwide.


Breast cancer in the young Ethnic differences China Asian breast cancer Biological characteristics 


Conflicts of interest



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Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2013

Authors and Affiliations

  • Muy-Kheng M. Tea
    • 1
    • 2
    Email author
  • Lei Fan
    • 1
  • James W. Delancey
    • 3
  • Christine Staudigl
    • 2
  • Stefan Steurer
    • 2
    • 4
  • Christina Lang
    • 2
  • Zhi-Ming Shao
    • 1
  • Christian F. Singer
    • 2
  1. 1.Department of Breast Surgery, Shanghai Cancer InstituteFudan UniversityShanghaiChina
  2. 2.Department of Obstetrics and GynecologyMedical University of ViennaViennaAustria
  3. 3.Department of Health Systems ManagementNew OrleansUSA
  4. 4.Institute for PathologyMedical University EppendorfHamburgGermany

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