Bone suppression for chest X-ray image using a convolutional neural filter
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Chest X-rays are used for mass screening for the early detection of lung cancer. However, lung nodules are often overlooked because of bones overlapping the lung fields. Bone suppression techniques based on artificial intelligence have been developed to solve this problem. However, bone suppression accuracy needs improvement. In this study, we propose a convolutional neural filter (CNF) for bone suppression based on a convolutional neural network which is frequently used in the medical field and has excellent performance in image processing. CNF outputs a value for the bone component of the target pixel by inputting pixel values in the neighborhood of the target pixel. By processing all positions in the input image, a bone-extracted image is generated. Finally, bone-suppressed image is obtained by subtracting the bone-extracted image from the original chest X-ray image. Bone suppression was most accurate when using CNF with six convolutional layers, yielding bone suppression of 89.2%. In addition, abnormalities, if present, were effectively imaged by suppressing only bone components and maintaining soft-tissue. These results suggest that the chances of missing abnormalities may be reduced by using the proposed method. The proposed method is useful for bone suppression in chest X-ray images.
KeywordsChest X-ray Bone suppression Lung Nodule Convolutional neural network Image processing
This research was partially supported by a Grant-in-Aid for Scientific Research on Innovative Areas (Multidisciplinary Computational Anatomy, No. 26108005) and a Grant-in-Aid for Scientific Research (No. 17K09070), MEXT, Japan.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
This article does not contain patient data.
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