Cardiovascular Engineering and Technology

, Volume 10, Issue 4, pp 618–627 | Cite as

Vascular Parameters for Ambulatory Monitoring of Congestive Heart Failure Patients: Proof of Concept

  • C. B. GoyEmail author
  • L. M. Yanicelli
  • N. Vargas
  • L. L. Lobo Marquez
  • J. Tazar
  • R. E. Madrid
  • M. C. Herrera
Original Article



Prompt detection of congestion is an essential target in order to prevent heart failure (HF) related hospitalization, being ambulatory monitoring a promising strategy to do so. A successful non-invasive ambulatory monitoring system requires automatic devices for physiological data recording; these data must give information about HF deterioration early enough to predict HF-related adverse events. This work aims to evaluate seven vascular parameters for the ambulatory monitoring of congestive heart failure patients.


Seven vascular parameters are proposed as indicators of HF deterioration. These parameters are obtained using venous occlusion plethysmography; a technique that uses hardware able of being miniaturized and easily integrated into wearables for ambulatory monitoring. The ability of the proposed vascular parameters to detect congestion is evaluated in eight healthy volunteers and ten congestive heart failure patients with different congestion levels—mild, moderate and severe.


Most parameters distinguish between healthy volunteers and heart failure patients, and some of them present significant differences between volunteers and low levels of congestion—mild or moderate.


Home monitoring of some of the proposed parameters could detect HF deterioration on its onset and alert to health personnel.


Venous occlusion plethysmography Decompensated heart failure Telemonitoring Wearables 



Analog–digital impedance plethysmograph


Analysis of variance


Blood flow


Venous compliance


Capillary filtration coefficient


Diastolic arterial pressure




Heart failure


Healthy volunteers


Mild congestion


Mean arterial pressure


Moderate congestion


Net fluid filtration


Occluder cuff




Systolic arterial pressure


Severe congestion


Systemic vascular resistance


Venous capacitance


Venous occlusion plethysmography


Conflict of interest

All authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments.

Supplementary material

13239_2019_432_MOESM1_ESM.docx (15 kb)
Supplementary material 1 (DOCX 14 kb)


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Copyright information

© Biomedical Engineering Society 2019

Authors and Affiliations

  1. 1.Laboratorio de Medios e Interfases (LAMEIN)-Departamento de Bioingeniería, Facultad de Ciencias Exactas y TecnologíaUniversidad Nacional de TucumánTucumánArgentina
  2. 2.Instituto Superior de Investigaciones Biológicas, Consejo Nacional de Investigaciones Científicas y TécnicasTucumánArgentina
  3. 3.Laboratorio de Investigaciones Cardiovasculares Multidisciplinarias-Departamento de Bioingeniería, Facultad de Ciencias Exactas y TecnologíaUniversidad Nacional de TucumánTucumánArgentina
  4. 4.Departamento de Ing. Eléctrica, Electrónica y Computación, Facultad de Ciencias Exactas y TecnologíaUniversidad Nacional de TucumánTucumánArgentina
  5. 5.Instituto de CardiologíaTucumánArgentina

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