Vascular Parameters for Ambulatory Monitoring of Congestive Heart Failure Patients: Proof of Concept
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Prompt detection of congestion is an essential target in order to prevent heart failure (HF) related hospitalization, being ambulatory monitoring a promising strategy to do so. A successful non-invasive ambulatory monitoring system requires automatic devices for physiological data recording; these data must give information about HF deterioration early enough to predict HF-related adverse events. This work aims to evaluate seven vascular parameters for the ambulatory monitoring of congestive heart failure patients.
Seven vascular parameters are proposed as indicators of HF deterioration. These parameters are obtained using venous occlusion plethysmography; a technique that uses hardware able of being miniaturized and easily integrated into wearables for ambulatory monitoring. The ability of the proposed vascular parameters to detect congestion is evaluated in eight healthy volunteers and ten congestive heart failure patients with different congestion levels—mild, moderate and severe.
Most parameters distinguish between healthy volunteers and heart failure patients, and some of them present significant differences between volunteers and low levels of congestion—mild or moderate.
Home monitoring of some of the proposed parameters could detect HF deterioration on its onset and alert to health personnel.
KeywordsVenous occlusion plethysmography Decompensated heart failure Telemonitoring Wearables
Analog–digital impedance plethysmograph
Analysis of variance
Capillary filtration coefficient
Diastolic arterial pressure
Mean arterial pressure
Net fluid filtration
Systolic arterial pressure
Systemic vascular resistance
Venous occlusion plethysmography
Conflict of interest
All authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments.
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