Cardiovascular Engineering and Technology

, Volume 7, Issue 3, pp 210–222 | Cite as

Time-Resolved Micro PIV in the Pivoting Area of the Triflo Mechanical Heart Valve

  • Bernhard M. VennemannEmail author
  • Thomas Rösgen
  • Thierry P. Carrel
  • Dominik Obrist


The Lapeyre-Triflo FURTIVA valve aims at combining the favorable hemodynamics of bioprosthetic heart valves with the durability of mechanical heart valves (MHVs). The pivoting region of MHVs is hemodynamically of special interest as it may be a region of high shear stresses, combined with areas of flow stagnation. Here, platelets can be activated and may form a thrombus which in the most severe case can compromise leaflet mobility. In this study we set up an experiment to replicate the pulsatile flow in the aortic root and to study the flow in the pivoting region under physiological hemodynamic conditions (CO = 4.5 L/min / CO = 3.0 L/min, f = 60 BPM). It was found that the flow velocity in the pivoting region could reach values close to that of the bulk flow during systole. At the onset of diastole the three valve leaflets closed in a very synchronous manner within an average closing time of 55 ms which is much slower than what has been measured for traditional bileaflet MHVs. Hot spots for elevated viscous shear stresses were found at the flanges of the housing and the tips of the leaflet ears. Systolic VSS was maximal during mid-systole and reached levels of up to 40 Pa.


μPIV Particle image velocimetry Mechanical heart valve Triflo furtiva valve High-speed imaging Gap flow Shear stress Hemodynamics 



The authors would like to thank Triflo Medical Switzerland Sarl for providing us with the Lapeyre-Triflo FURTIVA valve used in this project.

Conflict of Interest

Bernhard M. Vennemann, Thomas Rösgen, Thierry P. Carrel and Dominik Obrist declare that they have no conflict of interest.

Ethical Approval

No human and animal studies were carried out by the authors for this article.

Supplementary material

Supplementary material 1 (mp4 5,429 KB)

Supplementary material 2 (mp4 20,386 KB)


  1. 1.
    Bellhouse B. J. and F. H. Bellhouse. Mechanism of closure of the aortic valve. Nature 217: 86-87, 1968.CrossRefGoogle Scholar
  2. 2.
    Brucker C., U. Steinseifer, W. Schroder and H. Reul. Unsteady flow through a new mechanical heart valve prosthesis analysed by digital particle image velocimetry. Meas. Sci. Technol. 13: 1043-1049, 2002.CrossRefGoogle Scholar
  3. 3.
    Gallegos R. P., A. L. Rivard, P. T. Suwan, S. Black, S. Bertog, U. Steinseifer, A. Armien, M. Lahti and R. W. Bianco. In-vivo experience with the Triflo trileaflet mechanical heart valve. J. Heart Valve Dis. 15: 791-799, 2006.Google Scholar
  4. 4.
    Govindarajan V., H. S. Udaykumar and K. B. Chandran. Two-dimensional simulation of flow and platelet dynamics in the Hinge region of a mechanical heart valve. J. Biomech. Eng. T ASME 131, 2009.CrossRefGoogle Scholar
  5. 5.
    Gregoric I. D., K. Eya, D. Tamez, R. Cervera, D. Byler, J. Conger, E. Tuzun, H. K. Chee, F. J. Clubb, K. Kadipasaoglu and O. H. Frazier. Preclinical hemodynamic assessment of a new trileaflet mechanical valve in the aortic position in a bovine model. J. Heart Valve Dis. 13: 254-259, 2004.Google Scholar
  6. 6.
    Hoffmann G., G. Lutter and J. Cremer. Durability of bioprosthetic cardiac valves. Dtsch. Arztebl. Int. 105: 143-148, 2008.Google Scholar
  7. 7.
    Jun B. H., N. Saikrishnan and A. P. Yoganathan. Micro particle image velocimetry measurements of steady diastolic leakage flow in the hinge of a St. Jude Medical(R) regent mechanical heart valve. Ann. Biomed. Eng. 42: 526-540, 2014.CrossRefGoogle Scholar
  8. 8.
    Kaufmann T. A., T. Linde, E. Cuenca-Navalon, C. Schmitz, M. Hormes, T. Schmitz-Rode and U. Steinseifer. Transient, three-dimensional flow field simulation through a mechanical, trileaflet heart valve prosthesis. ASAIO J. 57: 278-282, 2011.CrossRefGoogle Scholar
  9. 9.
    Klusak E., A. Bellofiore, S. Loughnane and N. J. Quinlan. High-resolution measurements of velocity and shear stress in leakage jets from bileaflet mechanical heart valve Hinge models. J BIOMECH ENG-T ASME 137,2015.Google Scholar
  10. 10.
    Li C. P., S. F. Chen, C. W. Lo and P. C. Lu. Turbulence characteristics downstream of a new trileaflet mechanical heart valve. ASAIO J. 57: 188-196, 2011.CrossRefGoogle Scholar
  11. 11.
    Li C. P. and P. C. Lu. Numerical comparison of the closing dynamics of a new trileaflet and a bileaflet mechanical aortic heart valve. J. Artif. Organs 15: 364-374, 2012.CrossRefGoogle Scholar
  12. 12.
    Lu C. P. et al., The closing behavior of mechanical aortic heart valve prostheses. ASAIO J. 50:294-300, 2004CrossRefGoogle Scholar
  13. 13.
    Lu C. P. and P. C. Li, Numerical comparison of the closing dynamics of a new trileaflet and a bileaflet mechanical aortic heart valve. J. Artif. Organs 15:364-374, 2012CrossRefGoogle Scholar
  14. 14.
    Pedocchi F., J. E. Martin and M. H. Garcia. Inexpensive fluorescent particles for large-scale experiments using particle image velocimetry. Exp. Fluids 45: 183-186, 2008.CrossRefGoogle Scholar
  15. 15.
    Roudaut R., K. Serri and S. Lafitte. Thrombosis of prosthetic heart valves: diagnosis and therapeutic considerations. Heart 93: 137-142, 2007.CrossRefGoogle Scholar
  16. 16.
    Sato M., H. Harasaki, K. E. Wika, M. V. Soloviev and A. S. Lee. Blood compatibility of a newly developed trileaflet mechanical heart valve. ASAIO J. 49: 117-122, 2003.CrossRefGoogle Scholar
  17. 17.
    Sciacchitano A., F. Scarano and B. Wieneke. Multi-frame pyramid correlation for time-resolved PIV. Exp. Fluids 53: 1087-1105, 2012.CrossRefGoogle Scholar
  18. 18.
    Simon H. A., L. Ge, I. Borazjani, F. Sotiropoulos and A. P. Yoganathan. Simulation of the three-dimensional hinge flow fields of a bileaflet mechanical heart valve under aortic conditions. Ann. Biomed. Eng. 38: 841-853, 2010.CrossRefGoogle Scholar
  19. 19.
    Simon H. A., H. L. Leo, J. Carberry and A. P. Yoganathan. Comparison of the hinge flow fields of two bileaflet mechanical heart valves under aortic and mitral conditions. Ann. Biomed. Eng. 32: 1607-1617, 2004.CrossRefGoogle Scholar
  20. 20.
    Steinseifer U., C. Schmitz, T. Linde, T. Kaufmann and T. Schmitz-Rode. The Triflo trileaflet mechanical heart valve: design and in vitro performance. Int. J. Artif. Organs 32: 400-400, 2009.Google Scholar
  21. 21.
    Swanson W. M. and R. E. Clark. Dimensions and geometric relationships of human aortic value as a function of pressure. Circ. Res. 35: 871-882, 1974.CrossRefGoogle Scholar
  22. 22.
    Turina M., Supra-annular aortic valve replacement with a mechanical prosthesis Multimed. Man. Cardiothorac Surg. 1129:000083, 2005Google Scholar
  23. 23.
    Willert C., B. Stasicki, J. Klinner and S. Moessner. Pulsed operation of high-power light emitting diodes for imaging flow velocimetry. Meas. Sci. Technol. 21:075402, 2010.CrossRefGoogle Scholar

Copyright information

© Biomedical Engineering Society 2016

Authors and Affiliations

  • Bernhard M. Vennemann
    • 1
    • 2
    Email author
  • Thomas Rösgen
    • 1
  • Thierry P. Carrel
    • 3
  • Dominik Obrist
    • 2
  1. 1.Institute of Fluid DynamicsETH ZürichZurichSwitzerland
  2. 2.ARTORG CenterUniversity of BernBernSwitzerland
  3. 3.Department of Cardiovascular SurgeryBern University HospitalBernSwitzerland

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