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Polyploidy, body size, and opportunities for genetic enhancement and fixation of heterozygosity in plants

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Abstract

Polyploidy, the presence of more than two chromosome sets, is rare in animals, but is wide spread in plants. Polyploidy is believed to play an important role in speciation and diversification of plants. It is conjectured that almost all angiosperms are likely to be ancient polyploids i.e. palaeopolyploids that have undergone diploidization through differential mutation, elimination and inversion of duplicated chromosomes. Therefore, understanding of consequences of gene duplication on functional divergence, developmental behavior and genome stability is of utmost importance from utilitarian view point. Studies conducted by our group for over a quarter century on the cyotogenetics of polyploids on an array of medicinal and aromatic plants have enabled us to develop strategies to realize high fertility in the autotetraploids. It is surmised that pre-selection of diploid progenitor with low chiasmate association, preferably with distal chiasma localization facilitates high bivalent pairing and balanced meiotic segregation in the derived autotetraploid, and thereby promising high fertility. This has implications in ploidy mediated fixation of heterozygosity and genetic enhancement. However, the elevated ploidy level does not always bring about increase in body size. Both, increase or decrease in body size happen to occur consequent to genomic duplication, depending upon the species and composition of native secondary metabolites / cost of metabolic load. Of course, polyploidization does bring about increase in secondary metabolite concentration and DNA methylation. Further, the patterns of chromosome / ploidy variation encountered in callus cultures over passage of subcultures are indicative of variation happening over evolutionary timescale. The details concerning such issues are dealt in this article based on our own experimental observations and are discussed from utilitarian view point for further researches.

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References

  1. Arnold B, Bomblies K, Wakeley J. Extending coalescent theory to autotetraploids. Genetics. 2012;192:195–204.

    Google Scholar 

  2. Aversano R, Caruso I, Aronne G, DeMicco V, Scognamiglio N, Carputo D. Stochastic changes affect Solanum wild species following autopolyploidization. J Exp Bot. 2013;64:625–35.

    Google Scholar 

  3. Bowers JE, Chapman BA, Rong J, Paterson AH. Unraveling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events. Nature. 2003;422:433–8.

    Google Scholar 

  4. Chen ZJ. Genetic and epigenetic mechanisms for gene expression and phenotypic variation in plant polyploids. Annu Rev Plant Biol. 2007;58:377–406.

    Article  PubMed  CAS  Google Scholar 

  5. Ciu L, Wall PK, Leebens-Mack JH, Lindsay BG, Soltis DE, et al. Widespread genome duplications throughout the history of flowering plants. Genome Res. 2006;16:738–49.

    Google Scholar 

  6. Dhawan OP, Lavania UC. Enhancing the productivity of secondary metaboloites via induced polyploidy: a review. Euphytica. 1996;87:81–9.

    Google Scholar 

  7. Doyle JJ, Flagel LE, Paterson AH, Rapp RA, Soltis DE, Soltis PS, et al. Evolutionary genetics of genome merger and doubling in plants. Annu Rev Genet. 2008;42:443–61.

    Google Scholar 

  8. Galitski T, Saldanha AJ, Styles CA, Lander ES, Fink GR. Ploidy regulation of gene expression. Science. 1999;285:251–4.

    Google Scholar 

  9. Gaut BS. Patterns of chromosomal duplication in maize and their implications for comparative maps of the grasses. Genome Res. 2001;11:55–66.

    Google Scholar 

  10. Lavania UC. High bivalent frequencies in artificial autopolyploids of Hyoscyamus muticus L. Can J Genet Cytol. 1986;28:7–11.

    Google Scholar 

  11. Lavania UC. Genetic improvement of Egyptian henbane, Hyoscyamus muticus L. through induced tetraploidy. Theor Appl Genet. 1986;73:292–8.

    Google Scholar 

  12. Lavania UC. Genesis of high bivalent pairing in autotetraploids and autotriploids, and resuction in bound arm associations over generations. In: Brandham PE, Bennet MD, editors. Kew Chromosome Conf. IV. Royal Botanic Gardens, Kew; 1995. pp. 397–406.

  13. Lavania UC. Genomic and ploidy manipulation for enhanced production of phyto-pharmaceuticals. Plant Genet Resour. 2005;3:170–7.

    Article  CAS  Google Scholar 

  14. Lavania UC. Application of chromosome research in agricultural productivity of pharmaceuticals—Lessons from polyploidy. In: Yaniguchi K, Zhang X, editors. Advances in Chromosome Sciences. Tokyo; 2009. 3:6–10.

  15. Lavania UC, Srivastava S. Ploidy dependence of chromosomal variation in callus cultures of Hyoscyamus muticus L. Protoplasma. 1988;145:55–8.

    Google Scholar 

  16. Lavania UC, Srivastava S. Evolutionary genomic change paralleled by differential responses of 2× and 4× calli cultures. Experientia. 1990;46:322–4.

    Google Scholar 

  17. Lavania UC, Srivastava S, Sybenga J. Cytogenetics of fertility improvement in artificial autotetraploids of Hyoscyamus niger L. Genome. 1991;34:190–4.

    Google Scholar 

  18. Lavania UC, Srivastava S, Lavania S. Ploidy mediated reduced segregation facilitates fixation of heterozygosity in the aromatic grass, Cymbopogon martini (Roxb.). J Hered. 2010;101:119–23.

  19. Lavania UC, Srivastava S, Lavania S, Basu S, Misra NK, Mukai Y. Autopolyploidy differentially influences body size in plants, but facilitates enhanced accumulation of secondary metabolites, causing increased cytosine methylation. Plant J. 2012;71:539–549.

    Google Scholar 

  20. Levin DA. The role of chromosome change in plant evolution. New York: Oxford Univ. Press; 2002.

  21. Li X, Yu E, Fan C, Zhang C, Fu T, Zhou Y. Developmental, cytological and transcriptional analysis of autotetraploid Arabidopsis. Planta. 2012;236:579–96.

    Google Scholar 

  22. Mable BK. Breaking down taxonomic barriers in polyploidy research. Trends Plant Sci. 2003;8:582–90.

    Google Scholar 

  23. Masterson J. Stomatal size in fossil plants: evidence for polyploidy in majority of angiosperms. Science. 1994;264:421–4.

    Google Scholar 

  24. Nancy A, Eckardt NA. Two genomes are better than one: wide spread paleopolyploidy in plants and evolutionary effects. Plant Cell. 2004;16:1647–9.

    Google Scholar 

  25. Oswald BP, Nuismer SI. A unified model of autopolyploid establishment and evolution. Am Nat. 2011;178:687–700.

    Google Scholar 

  26. Otto SP. The evolutionary consequences of polyploidy. Cell. 2007;131:452.

    Google Scholar 

  27. Parisod C, Holderegger R, Brochmann C. Evolutionary consequences of autopolyploidy. New Phytol. 2010;186:5–17.

    Google Scholar 

  28. Paterson AH. Polyploidy, evolutionary opportunity, and crop adaptation. Genetica. 2005;123:191–6.

    Google Scholar 

  29. Semon M, Wolfe KH. Consequences of genome duplication. Curr Opin Genet Dev. 2007;17:505–12.

    Google Scholar 

  30. Soltis DE, Soltis PS. Polyploidy: recurrent formation and genome evolution. Trends Ecol Evol. 1999;14:348–52.

    Google Scholar 

  31. Soltis DE, Soltis PS, Schemske DW, Hancock JF, Thompson JN, et al. Autopolyploidy in angiosperms: have we grossly underestimated the number of species? Taxon. 2007;56:13–30.

  32. Srivastava S, Lavania UC, Sybenga J. Genetic variation in meiotic behaviour and fertility in tetraploid Hyoscyamus muticus: correlation with diploid meiosis. Heredity. 1992;68:231–9.

    Google Scholar 

  33. te Beest M, Le Roux JJ, Richardson DM, Brysting AK, Suda J, Kubesova M, et al. The more the better? The role of polyploidy infacilitating plant invasions. Ann Bot. 2012;109:19–45.

    Google Scholar 

  34. Udall JA, Wendel JF. Polyploidy and crop improvement. Crop Sci. 2006;46:3–14.

    Google Scholar 

  35. Vision TJ, Brown DG, Tanksley SD. The origins of genomic duplications in Arabidopsis. Science. 2000;290:2114–7.

    Google Scholar 

  36. Wendel JF. Genome evolution in polyploids. Plant Mol Biol. 2000;42:225–49.

    Google Scholar 

  37. Wolfe KH. Yesterday’s polyploidization and the mystery of diploidization. Nat Rev Genet. 2001;2:333–41.

    Google Scholar 

  38. Wood TE, Takebayashi N, Barker MS, Mayrose I, Greenspoon PB, et al. The frequency of polyploid speciation in vascular plants. Proc Natl Acad Sci USA. 2009;106:13875–9.

    Google Scholar 

  39. Yang X, Ye C-Y, Cheng Z-M, Tschaplinski TJ, Wullschleger SD, Yin W, et al. Genomic aspects of research involving polyploid plants. Plant Cell Tissue Organ Cult. 2011;104:387–97.

    Google Scholar 

  40. Yu J, Wang J, Lin W, Li S, Li H, et al. The genomes of Oryza sativa: a history of duplications. PLoS Biol. 2005;3:e38.

    Google Scholar 

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Acknowledgment

The Indian Science Congress Association, Kolkata is gratefully acknowledged for the necessary permission for this publication.

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  1. CSIR - Central Institute of Medicinal and Aromatic Plants, Lucknow, 226 015, India

    Umesh C. Lavania

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  1. Umesh C. Lavania
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Correspondence to Umesh C. Lavania.

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Based on the Presidential address delivered on 4th January 2013 at the Plant Sciences section of the Centenary session of Indian Science Congress held at Kolkata, pages 1–12. This article is dedicated in memory of Professor (Mrs.) Archana Sharma

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Lavania, U.C. Polyploidy, body size, and opportunities for genetic enhancement and fixation of heterozygosity in plants. Nucleus 56, 1–6 (2013). https://doi.org/10.1007/s13237-013-0075-7

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