Annals of Microbiology

, Volume 62, Issue 1, pp 1–5 | Cite as

Enterobacter sakazakii: an emerging foodborne pathogenic bacterium

  • XianFeng ZhouEmail author
  • SongZhe Fu
  • JianXin Gao
  • HaiYing Chen


Enterobacter sakazakii (Cronobacter spp.) is an emerging pathogen associated with the ingestion of contaminated powdered infant formula (PIF) that causes necrotizing enterocolitis, sepsis, and meningitis in low-birth-weight preterm neonatal infants. The natural habitat of E. sakazakii is unknown, but PIF has been suggested as a possible mode of transmission in neonatal infections. The presence of E. sakazakii is not limited to powdered infant formula, it can also be found in a broad range of foods and in water. In recent years, the International Commission on Microbiological Specifications for Foods has ranked E. sakazakii a “severe hazard for restricted populations.” The present review is mainly focused on environmental stress on E. sakazakii and its antibiotic resistance.


Enterobacter sakazakii Powdered infant formula Neonatal infections Environmental stress Antibiotic resistance 


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Copyright information

© Springer-Verlag and the University of Milan 2011

Authors and Affiliations

  • XianFeng Zhou
    • 1
    Email author
  • SongZhe Fu
    • 1
  • JianXin Gao
    • 1
  • HaiYing Chen
    • 1
    • 2
  1. 1.Nanchang Center for Disease Control and PreventionNanchangChina
  2. 2.Medical College of Nanchang UniversityNanchangChina

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