3 Biotech

, 10:106 | Cite as

A bibliometric-based analysis of the high-value application of Chlorella

  • Ziliang Cheng
  • Weibao KongEmail author
  • Ziwen Cheng
  • Huifang Qi
  • Shuling Yang
  • Aimei Zhang
  • Shiquan Niu
Original Article


This bibliometric-based review analyses the trends in 1010 published articles (1990 to mid-2018) on the high-value application of Chlorella, and illustrates the evolution and latest tendencies at a global level by the number of publications and their distribution, issuing institutions and countries or regions, the sources and research direction, as well as the core-author and keywords. The results demonstrated that there is a burst in terms of the number of articles, and China, USA, Mexico, and Japan are the dominant countries in this area. The most relevant journals with this subject are Bioresource Technology and Hydrobiology, and the research mainly focuses on marine and freshwater biology, biotechnology and applied microbiology, energy and fuels, food science and technology, and environmental sciences. Overall, bibliometric analysis has shown that Chlorella application research is a very active field, and the future research will be conducted into construction of genetic engineering algae, high-density and low-cost culture systems, efficient harvesting and separation techniques, effective energy conversion, integrated photo-bioreactors, and molecular biology technology. Wastewater treatment, CO2 bio-fixation, biomass production, and biosynthesis of useful substances by cultivating microalgae are promising research fields.


Chlorella High-value application Bibliometric maps Citation Biofuels 


Author contributions

CZL and KWB conceived structure and wrote the manuscript. CZW designed the chart,and analysed data with CZL and KWB. QHF and YSL gave some valuable advices about of manuscript. ZAM and NSQ revised the manuscript. All authors read and approved the final manuscript.


This work was supported by the National Natural Science Foundation of China (No. 31360192).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© King Abdulaziz City for Science and Technology 2020

Authors and Affiliations

  1. 1.College of Life ScienceNorthwest Normal UniversityLanzhouChina
  2. 2.College of Mechanical EngineeringZhejiang University of TechnologyHangzhouChina

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