3 Biotech

, 8:309 | Cite as

Plants in traditional medicine with special reference to Cyperus rotundus L.: a review

  • Arunagiri Kamala
  • Sushil Kumar MiddhaEmail author
  • Chandrakant S. Karigar
Review Article


The nutgrass, Cyperus rotundus L. (Family: Cyperaceae), is a colonial, perennial herb considered to have originated in India 2000 years ago and widely used in Ayurveda to treat several ailments. In addition to its prehistoric uses, it is used in several systems of medicine for treating variety of diseases. The synergistic actions of the Cyperus’ compounds have added advantage over that of a single constituent. In the past decade, numerous studies proved analgesic, anti-allergic, anti-arthritic, anti-candida, anti-cariogenic, anti-convulsant, anti-diarrheal, anti-emetic, anti-helminthic, anti-histamine, anti-hyperglycemic, anti-hypertensive, anti-inflammatory, anti-malarial, anti-obesity, antioxidant, anti-platelet, anti-pyretic, anti-ulcer, anti-viral, cardioprotective, cytoprotective, cytotoxic, gastroprotective, hepatoprotective, neuroprotective, ovicidal, and larvicidal, wound healing and inhibition of brain Na+ K+ ATPase activities of C. rotundus and its chemical constituents. However, the exact the mechanism of action is not very clear and requires further evaluation. These properties strongly suggest an extensive use of C. rotundus for clinical applications. In this review, we attempted to provide information about the pharmacological effects of Cyperus and its proposed mechanisms of actions.


Ayurveda Nutgrass Pharmacological activity Secondary metabolites Traditional medicine 



World Health Organization

C. rotundus L

Cyperus rotundus L


Body weight


Compliance with ethical standards

Conflict of interest

Authors declare no conflict of interest.

Supplementary material

13205_2018_1328_MOESM1_ESM.docx (289 kb)
Supplementary material 1 (DOCX 288 KB)


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Arunagiri Kamala
    • 1
  • Sushil Kumar Middha
    • 2
    Email author
  • Chandrakant S. Karigar
    • 1
    • 3
  1. 1.Department of Studies and Research in BiochemistryTumkur UniversityTumkurIndia
  2. 2.DBT-BIF Facility, Department of BiotechnologyMaharani Lakshmi Ammanni College for WomenBangaloreIndia
  3. 3.Department of BiochemistryBangalore UniversityBangaloreIndia

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